ABATACEPT

Search structure
Trade Names:
Synonyms:
Status: Approved (2006)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: L04AA24
UNII: 7D0YB67S97

Pharmacology

Action Mechanism of Action Reference
INHIBITOR T-lymphocyte activation antigen CD80 inhibitor DailyMed
Primary Target
CD80
CD86

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Arthritis, Rheumatoid 4 D001172 ClinicalTrials
Arthritis, Psoriatic 4 D015535 ClinicalTrials
Arthritis, Juvenile 4 D001171 ClinicalTrials
Severe Acute Respiratory Syndrome 3 D045169 ClinicalTrials
Sjogren's Syndrome 3 D012859 ClinicalTrials
Polymyalgia Rheumatica 3 D011111 ClinicalTrials
Giant Cell Arteritis 3 D013700 ClinicalTrials
Lupus Nephritis 3 D008181 ClinicalTrials
Crohn Disease 3 D003424 ClinicalTrials
Granulomatosis with Polyangiitis 3 D014890 ClinicalTrials
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 3 D056648 ClinicalTrials
Dermatomyositis 3 D003882 ClinicalTrials
Colitis, Ulcerative 3 D003093 ClinicalTrials
Peanut Hypersensitivity 2 D021183 ClinicalTrials
Lupus Erythematosus, Systemic 2 D008180 ClinicalTrials
Spondylitis, Ankylosing 2 D013167 ClinicalTrials
Multiple Sclerosis 2 D009103 ClinicalTrials
Hypertension 2 D006973 ClinicalTrials
Alopecia Areata 2 D000506 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Alopecia 2 D000505 ClinicalTrials
Psoriasis 2 D011565 ClinicalTrials
Sarcoidosis 2 D012507 ClinicalTrials
Multiple Sclerosis, Relapsing-Remitting 2 D020529 ClinicalTrials
Nephrotic Syndrome 2 D009404 ClinicalTrials
Uveitis 2 D014605 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Immunoglobulin G4-Related Disease 2 D000077733 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Scleroderma, Diffuse 2 D045743 ClinicalTrials
Multiple Myeloma 2 D009101 ClinicalTrials
Psoriasis 2 D011565 ClinicalTrials
Takayasu Arteritis 2 D013625 ClinicalTrials
Polychondritis, Relapsing 1 D011081 ClinicalTrials
Vitiligo 1 D014820 ClinicalTrials
Myasthenia Gravis 0 D009157 ClinicalTrials
Behcet Syndrome 0 D001528 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
15.74
Musculoskeletal and connective tissue disorders
12.09
Infections and infestations
8.99
Respiratory, thoracic and mediastinal disorders
8.81
Injury, poisoning and procedural complications
8.3
Gastrointestinal disorders
6.3
Nervous system disorders
5.63
Skin and subcutaneous tissue disorders
5.58
Vascular disorders
4.09
Immune system disorders
3.78
Cardiac disorders
3.27
Investigations
2.83
Surgical and medical procedures
2.3

Cross References

Resources Reference
CAS NUMBER 332348-12-6
ChEMBL CHEMBL1201823
FDA SRS 7D0YB67S97
Guide to Pharmacology 6891
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