DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 61


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY ORAL Osteomyelitis; Glioblastoma; Hypertension, Pulmonary; Intestinal Obstruction; Nausea; Cholangitis, Sclerosing; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY ORAL Alzheimer Disease; Depression; Depressive Disorder; Depressive Disorder, Major Monoamine oxidase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Metabolic Syndrome; Diabetes Mellitus; Lecithin Cholesterol Acyltransferase Deficiency; Kidney Diseases; Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Kidney Calculi; Pre-Eclampsia; Angina Pectoris; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Myocardial Infarction; Nephrotic Syndrome; Renal Insufficiency, Chronic; Toxemia Thiazide-sensitive sodium-chloride cotransporter inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Metabolic Syndrome; Diabetes Mellitus; Lecithin Cholesterol Acyltransferase Deficiency; Kidney Diseases; Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Kidney Calculi; Pre-Eclampsia; Angina Pectoris; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Myocardial Infarction; Nephrotic Syndrome; Renal Insufficiency, Chronic; Toxemia

Thiazide-sensitive sodium-chloride cotransporter inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER BUCCAL; IMPLANTATION; INJECTION; NASAL; TRANSDERMAL Cerebral Arterial Diseases; Dyspareunia; Insulin Resistance; Polycystic Ovary Syndrome; Aging; Kallmann Syndrome; Penile Induration; Acquired Immunodeficiency Syndrome; Anorexia Nervosa; Dwarfism; Heart Failure; Hereditary Breast and Ovarian Cancer Syndrome; Menopause; Multiple Sclerosis; Muscular Diseases; Obesity; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcopenia; Spinal Cord Injuries; Testicular Neoplasms; Coronary Disease; Disorders of Sex Development; Erectile Dysfunction; Hip Fractures; Infertility; Metabolic Syndrome; Neoplasms; Renal Insufficiency, Chronic; Sexual Dysfunction, Physiological; Hypogonadism; Klinefelter Syndrome; Orchitis Androgen Receptor agonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

BUCCAL; IMPLANTATION; INJECTION; NASAL; TRANSDERMAL

Cerebral Arterial Diseases; Dyspareunia; Insulin Resistance; Polycystic Ovary Syndrome; Aging; Kallmann Syndrome; Penile Induration; Acquired Immunodeficiency Syndrome; Anorexia Nervosa; Dwarfism; Heart Failure; Hereditary Breast and Ovarian Cancer Syndrome; Menopause; Multiple Sclerosis; Muscular Diseases; Obesity; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcopenia; Spinal Cord Injuries; Testicular Neoplasms; Coronary Disease; Disorders of Sex Development; Erectile Dysfunction; Hip Fractures; Infertility; Metabolic Syndrome; Neoplasms; Renal Insufficiency, Chronic; Sexual Dysfunction, Physiological; Hypogonadism; Klinefelter Syndrome; Orchitis

Androgen Receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER INJECTION; INTRAMUSCULAR; SUBCUTANEOUS Pregnancy; Premature Birth Progesterone receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY ORAL; TOPICAL; TRANSDERMAL; VAGINAL Cerebral Arterial Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; HIV Infections; Osteoporosis; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Amenorrhea; Anorexia Nervosa; Atrophic Vaginitis; Atrophy; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Endometriosis; Hot Flashes; Infertility; Leiomyoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Dyspareunia; Hypogonadism; Primary Ovarian Insufficiency Estrogen receptor alpha agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY

ORAL; TOPICAL; TRANSDERMAL; VAGINAL

Cerebral Arterial Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; HIV Infections; Osteoporosis; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Amenorrhea; Anorexia Nervosa; Atrophic Vaginitis; Atrophy; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Endometriosis; Hot Flashes; Infertility; Leiomyoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Dyspareunia; Hypogonadism; Primary Ovarian Insufficiency

Estrogen receptor alpha agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; INTRAUTERINE; ORAL; VAGINAL Diabetes Mellitus, Type 1; Anorexia Nervosa; Bulimia Nervosa; Cervical Intraepithelial Neoplasia; Cocaine-Related Disorders; Coronary Disease; Depression, Postpartum; Endometrial Neoplasms; HIV Infections; Marijuana Abuse; Orthostatic Intolerance; Placenta Previa; Polycystic Ovary Syndrome; Pre-Eclampsia; Severe Acute Respiratory Syndrome; Tobacco Use Disorder; Vulvar Lichen Sclerosus; Alzheimer Disease; Angina, Unstable; Bone Diseases, Metabolic; Brain Injuries; Breast Neoplasms; Diabetes Mellitus; Epilepsy; Hypercholesterolemia; Hypertension; Infertility; Infertility, Female; Leiomyoma; Memory Disorders; Menopause; Myocardial Ischemia; Osteoporosis; Ovarian Hyperstimulation Syndrome; Pregnancy; Premature Birth; Thrombosis; Amenorrhea; Endometrial Hyperplasia; Hemorrhage; Uterine Hemorrhage Progesterone receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; INTRAUTERINE; ORAL; VAGINAL

Diabetes Mellitus, Type 1; Anorexia Nervosa; Bulimia Nervosa; Cervical Intraepithelial Neoplasia; Cocaine-Related Disorders; Coronary Disease; Depression, Postpartum; Endometrial Neoplasms; HIV Infections; Marijuana Abuse; Orthostatic Intolerance; Placenta Previa; Polycystic Ovary Syndrome; Pre-Eclampsia; Severe Acute Respiratory Syndrome; Tobacco Use Disorder; Vulvar Lichen Sclerosus; Alzheimer Disease; Angina, Unstable; Bone Diseases, Metabolic; Brain Injuries; Breast Neoplasms; Diabetes Mellitus; Epilepsy; Hypercholesterolemia; Hypertension; Infertility; Infertility, Female; Leiomyoma; Memory Disorders; Menopause; Myocardial Ischemia; Osteoporosis; Ovarian Hyperstimulation Syndrome; Pregnancy; Premature Birth; Thrombosis; Amenorrhea; Endometrial Hyperplasia; Hemorrhage; Uterine Hemorrhage

Progesterone receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER INJECTION; INTRACRANIAL Leukemia, Plasma Cell; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neuroblastoma; Sezary Syndrome; Brain Neoplasms; Colorectal Neoplasms; Gliosarcoma; Hematologic Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Ovarian Neoplasms; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stiff-Person Syndrome; Breast Neoplasms; Central Nervous System Neoplasms; Leukemia; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Oligodendroglioma; Astrocytoma; Ependymoma; Glioblastoma; Glioma; Hodgkin Disease; Medulloblastoma; Multiple Myeloma; Neoplasms DNA inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

INJECTION; INTRACRANIAL

Leukemia, Plasma Cell; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neuroblastoma; Sezary Syndrome; Brain Neoplasms; Colorectal Neoplasms; Gliosarcoma; Hematologic Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Ovarian Neoplasms; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stiff-Person Syndrome; Breast Neoplasms; Central Nervous System Neoplasms; Leukemia; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Oligodendroglioma; Astrocytoma; Ependymoma; Glioblastoma; Glioma; Hodgkin Disease; Medulloblastoma; Multiple Myeloma; Neoplasms

DNA inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER ORAL Atrophy; Breast Neoplasms; Hypogonadism; Menopause; Primary Ovarian Insufficiency Estrogen receptor agonist


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left

Angiotensin-converting enzyme inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Depressive Disorder; Depressive Disorder, Major; Cardiovascular Diseases Beta-1 adrenergic receptor partial agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; HEMATOLOGY; OTHER ORAL Angina, Stable; Ischemic Stroke; Spinal Cord Injuries; Brain Injuries; Diabetes Mellitus, Type 1; Stroke; Diabetes, Gestational; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Atherosclerosis; Renal Insufficiency, Chronic; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS INJECTION Unknown Growth hormone-releasing hormone receptor agonist


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; HEMATOLOGY; OTHER UNKNOWN Myasthenia Gravis; Adenocarcinoma; Anemia, Refractory, with Excess of Blasts; Arthritis, Rheumatoid; Carcinoma, Hepatocellular; Endometrial Neoplasms; Glioma; Hepatitis B, Chronic; Leukemia, Plasma Cell; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Parkinson Disease; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triple Negative Breast Neoplasms; Alzheimer Disease; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Cystadenoma, Serous; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; HIV Infections; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Peripheral Arterial Disease; Peritoneal Neoplasms; Prostatic Neoplasms; Pulmonary Alveolar Proteinosis; Rectal Neoplasms; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Crohn Disease; Cytomegalovirus Retinitis; Fever; Graft vs Host Disease; Hematologic Diseases; Infections; Leishmaniasis, Cutaneous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Mesenchymoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Neutropenia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma; Sarcoma; Sepsis; Urinary Bladder Neoplasms; Leukemia, Myeloid, Acute Granulocyte-macrophage colony-stimulating factor receptor agonist

Protein

Approved

DIABETES DRUGS & ENDOCRINOLOGY; HEMATOLOGY; OTHER

UNKNOWN

Myasthenia Gravis; Adenocarcinoma; Anemia, Refractory, with Excess of Blasts; Arthritis, Rheumatoid; Carcinoma, Hepatocellular; Endometrial Neoplasms; Glioma; Hepatitis B, Chronic; Leukemia, Plasma Cell; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Parkinson Disease; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triple Negative Breast Neoplasms; Alzheimer Disease; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Cystadenoma, Serous; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; HIV Infections; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Peripheral Arterial Disease; Peritoneal Neoplasms; Prostatic Neoplasms; Pulmonary Alveolar Proteinosis; Rectal Neoplasms; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Crohn Disease; Cytomegalovirus Retinitis; Fever; Graft vs Host Disease; Hematologic Diseases; Infections; Leishmaniasis, Cutaneous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Mesenchymoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Neutropenia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma; Sarcoma; Sepsis; Urinary Bladder Neoplasms; Leukemia, Myeloid, Acute

Granulocyte-macrophage colony-stimulating factor receptor agonist


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS INJECTION; SUBCUTANEOUS Prostatic Neoplasms Gonadotropin-releasing hormone receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Colorectal Neoplasms; Muscular Diseases; Pain; Sprains and Strains; Acute Pain; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved DERMATOLOGY; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hyperplasia; Hypogonadism; Acne Vulgaris; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms, Castration-Resistant; Retinal Diseases; Alopecia; Prostatic Hyperplasia; Prostatic Neoplasms Steroid 5-alpha-reductase 2 inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cholangitis, Sclerosing; Alcoholism; Burns; Diabetic Nephropathies; HIV Infections; Huntington Disease; Metabolic Syndrome; Multiple Myeloma; Non-alcoholic Fatty Liver Disease; Obesity; Atherosclerosis; Coronary Disease; Diabetic Retinopathy; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemias; Hyperlipoproteinemia Type III; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Lipodystrophy; Liver Cirrhosis, Biliary; Metabolic Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyslipidemias; Hypercholesterolemia; Hypothyroidism Peroxisome proliferator-activated receptor alpha agonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Cholangitis, Sclerosing; Alcoholism; Burns; Diabetic Nephropathies; HIV Infections; Huntington Disease; Metabolic Syndrome; Multiple Myeloma; Non-alcoholic Fatty Liver Disease; Obesity; Atherosclerosis; Coronary Disease; Diabetic Retinopathy; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemias; Hyperlipoproteinemia Type III; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Lipodystrophy; Liver Cirrhosis, Biliary; Metabolic Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyslipidemias; Hypercholesterolemia; Hypothyroidism

Peroxisome proliferator-activated receptor alpha agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS ORAL Acidosis, Lactic; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; AIDS Dementia Complex; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved DERMATOLOGY; DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INJECTION; ORAL; TOPICAL Neoplasms, Neuroepithelial; Alopecia; Aspergillosis; beta-Thalassemia; Blast Crisis; DiGeorge Syndrome; Hematologic Diseases; Hypercholesterolemia; Kidney Tubular Necrosis, Acute; Leukemia, Plasma Cell; Lymphedema; Lymphoma, T-Cell; Paget Disease, Extramammary; Peripheral Nerve Injuries; Respiratory Syncytial Virus Infections; Scleroderma, Localized; Vasculitis; Venous Thromboembolism; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Sickle Cell; Asthma; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Colitis; Crohn Disease; Diabetes Mellitus; Edema; Encephalomyelitis; Epidermolysis Bullosa; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Hepatitis, Autoimmune; Hepatitis C; Hepatitis C, Chronic; Histiocytosis, Langerhans-Cell; Hypertension, Pulmonary; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Lichen Planus, Oral; Liver Diseases; Liver Failure; Lung Diseases; Lupus Erythematosus, Cutaneous; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Multiple Myeloma; Multiple Sclerosis; Mycosis Fungoides; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms; Nephrosis, Lipoid; Neuroblastoma; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Purpura, Thrombocytopenic, Idiopathic; Sarcoma; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Thalassemia; Vulvar Lichen Sclerosus; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Wounds and Injuries; Arthritis, Rheumatoid; Bronchiolitis Obliterans; Carcinoma, Hepatocellular; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis, Atopic; Dermatitis, Seborrheic; Diabetes Mellitus, Type 1; Glomerulonephritis, Membranous; Graft vs Host Disease; Heart Diseases; Hodgkin Disease; Infertility; Keratoconjunctivitis; Kidney Diseases; Lupus Nephritis; Lymphoma, Non-Hodgkin; Myasthenia Gravis; Myelodysplastic Syndromes; Nephrotic Syndrome; Psoriasis; Renal Insufficiency; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Skin Neoplasms; Vitiligo; Eczema; Immune System Diseases FK506-binding protein 1A inhibitor

Small molecule

Approved

DERMATOLOGY; DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY

INJECTION; ORAL; TOPICAL

Neoplasms, Neuroepithelial; Alopecia; Aspergillosis; beta-Thalassemia; Blast Crisis; DiGeorge Syndrome; Hematologic Diseases; Hypercholesterolemia; Kidney Tubular Necrosis, Acute; Leukemia, Plasma Cell; Lymphedema; Lymphoma, T-Cell; Paget Disease, Extramammary; Peripheral Nerve Injuries; Respiratory Syncytial Virus Infections; Scleroderma, Localized; Vasculitis; Venous Thromboembolism; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Sickle Cell; Asthma; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Colitis; Crohn Disease; Diabetes Mellitus; Edema; Encephalomyelitis; Epidermolysis Bullosa; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Hepatitis, Autoimmune; Hepatitis C; Hepatitis C, Chronic; Histiocytosis, Langerhans-Cell; Hypertension, Pulmonary; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Lichen Planus, Oral; Liver Diseases; Liver Failure; Lung Diseases; Lupus Erythematosus, Cutaneous; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Multiple Myeloma; Multiple Sclerosis; Mycosis Fungoides; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms; Nephrosis, Lipoid; Neuroblastoma; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Purpura, Thrombocytopenic, Idiopathic; Sarcoma; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Thalassemia; Vulvar Lichen Sclerosus; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Wounds and Injuries; Arthritis, Rheumatoid; Bronchiolitis Obliterans; Carcinoma, Hepatocellular; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis, Atopic; Dermatitis, Seborrheic; Diabetes Mellitus, Type 1; Glomerulonephritis, Membranous; Graft vs Host Disease; Heart Diseases; Hodgkin Disease; Infertility; Keratoconjunctivitis; Kidney Diseases; Lupus Nephritis; Lymphoma, Non-Hodgkin; Myasthenia Gravis; Myelodysplastic Syndromes; Nephrotic Syndrome; Psoriasis; Renal Insufficiency; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Skin Neoplasms; Vitiligo; Eczema; Immune System Diseases

FK506-binding protein 1A inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hypotension, Orthostatic; Nesidioblastosis; Obesity; Aging; Non-alcoholic Fatty Liver Disease; Atherosclerosis; Coronary Disease; Diabetes, Gestational; Hypercholesterolemia; Hypertension; Metabolic Diseases; Metabolic Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2 Maltase-glucoamylase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Atherosclerosis; Coronary Disease; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER INJECTION Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Nasopharyngeal Neoplasms; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia Reactive metabolite scavenging agent

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

INJECTION

Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Nasopharyngeal Neoplasms; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia

Reactive metabolite scavenging agent


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER ORAL Alzheimer Disease; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases DNA inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

ORAL

Alzheimer Disease; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases

DNA inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Breast Neoplasms; Obesity; Substance-Related Disorders; Cocaine-Related Disorders; Endometriosis; Infertility; Paget Disease, Extramammary; Pituitary ACTH Hypersecretion; Acromegaly; Diabetes Mellitus; Ovarian Hyperstimulation Syndrome; Restless Legs Syndrome; Parkinson Disease; Pituitary Neoplasms

Dopamine D2 receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Fibromyalgia; Glioma; Substance-Related Disorders; Weight Loss; Anorexia; Anxiety; Cachexia; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders

Adrenergic receptor alpha-2 antagonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Severe Acute Respiratory Syndrome; Acute Coronary Syndrome; Cardiomyopathy, Hypertrophic; Nephritis, Hereditary; Peripheral Arterial Disease; Renal Insufficiency, Chronic; Atherosclerosis; Atrial Fibrillation; Chagas Cardiomyopathy; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Pulmonary; Kidney Diseases; Lipid Metabolism Disorders; Metabolic Syndrome; Non-ST Elevated Myocardial Infarction; ST Elevation Myocardial Infarction; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke; Ventricular Dysfunction, Left

Type-1 angiotensin II receptor antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 1; Diabetes Mellitus; Diabetes Mellitus, Type 2 Lysosomal alpha-glucosidase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Gastrointestinal Stromal Tumors; Mitochondrial Diseases; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Atherosclerosis; Coronary Disease; Cystic Fibrosis; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker

Antibody

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

SINGLE-USE

DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Immune System Diseases

Interleukin-2 receptor inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic

Vitamin D receptor agonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY

ORAL

Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis

Dihydroorotate dehydrogenase inhibitor