DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 29


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Amyotrophic Lateral Sclerosis; Anxiety Disorders; Infections; Pulmonary Disease, Chronic Obstructive; Breast Carcinoma In Situ; Breast Neoplasms; Endometrial Neoplasms; Protoporphyria, Erythropoietic; Dermatitis, Atopic; Gastrointestinal Hemorrhage; Hemorrhage; Ulcer; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer Histamine H2 receptor antagonist

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL

Amyotrophic Lateral Sclerosis; Anxiety Disorders; Infections; Pulmonary Disease, Chronic Obstructive; Breast Carcinoma In Situ; Breast Neoplasms; Endometrial Neoplasms; Protoporphyria, Erythropoietic; Dermatitis, Atopic; Gastrointestinal Hemorrhage; Hemorrhage; Ulcer; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer

Histamine H2 receptor antagonist


Small molecule Approved CARDIOVASCULAR; GASTROINTESTINAL; OTHER INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL Colorectal Neoplasms; Hypertension, Pulmonary; Hypotension; Infections; Inflammation; Peripheral Arterial Disease; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Pulmonary Edema; Shock; Tendinopathy; Anus Diseases; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Heart Diseases; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain Soluble guanylate cyclase activator

Small molecule

Approved

CARDIOVASCULAR; GASTROINTESTINAL; OTHER

INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL

Colorectal Neoplasms; Hypertension, Pulmonary; Hypotension; Infections; Inflammation; Peripheral Arterial Disease; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Pulmonary Edema; Shock; Tendinopathy; Anus Diseases; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Heart Diseases; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain

Soluble guanylate cyclase activator


Small molecule Approved GASTROINTESTINAL ORAL Carcinoma, Medullary; Esophagitis, Peptic; Hypotension, Orthostatic; Immune System Diseases; Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma, Renal Cell; Helicobacter Infections; Job Syndrome; Leukemia, T-Cell; Postpartum Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Barrett Esophagus; Cough; Multiple Sclerosis; Stomach Ulcer; Gastroesophageal Reflux; Peptic Ulcer Histamine H2 receptor antagonist

Small molecule

Approved

GASTROINTESTINAL

ORAL

Carcinoma, Medullary; Esophagitis, Peptic; Hypotension, Orthostatic; Immune System Diseases; Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma, Renal Cell; Helicobacter Infections; Job Syndrome; Leukemia, T-Cell; Postpartum Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Barrett Esophagus; Cough; Multiple Sclerosis; Stomach Ulcer; Gastroesophageal Reflux; Peptic Ulcer

Histamine H2 receptor antagonist


Small molecule Approved GASTROINTESTINAL; IMMUNE SYSTEM; OTHER INHALATION; ORAL Breast Neoplasms; Neoplasms; Diabetes Mellitus, Type 1; Encephalitis, Japanese; Hemorrhagic Fever with Renal Syndrome; Hepatitis D; Influenza, Human; Lassa Fever; Leukemia, Myeloid, Acute; Thrombocytopenia; Depressive Disorder; Hepatitis; Hepatitis B, Chronic; Hepatitis C; HIV Infections; Infections; Respiratory Syncytial Virus Infections; Severe Acute Respiratory Syndrome; Fibrosis; Hepatitis C, Chronic; Liver Cirrhosis; Virus Diseases Inosine-5'-monophosphate dehydrogenase 1 inhibitor

Small molecule

Approved

GASTROINTESTINAL; IMMUNE SYSTEM; OTHER

INHALATION; ORAL

Breast Neoplasms; Neoplasms; Diabetes Mellitus, Type 1; Encephalitis, Japanese; Hemorrhagic Fever with Renal Syndrome; Hepatitis D; Influenza, Human; Lassa Fever; Leukemia, Myeloid, Acute; Thrombocytopenia; Depressive Disorder; Hepatitis; Hepatitis B, Chronic; Hepatitis C; HIV Infections; Infections; Respiratory Syncytial Virus Infections; Severe Acute Respiratory Syndrome; Fibrosis; Hepatitis C, Chronic; Liver Cirrhosis; Virus Diseases

Inosine-5'-monophosphate dehydrogenase 1 inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL; RECTAL Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Digestive System Diseases; Diverticulum, Colon; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis Arachidonate 5-lipoxygenase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL; RECTAL

Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Digestive System Diseases; Diverticulum, Colon; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis

Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER; RESPIRATORY INJECTION; ORAL; OTIC Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections Bacterial DNA gyrase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INJECTION; ORAL; OTIC

Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections

Bacterial DNA gyrase inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Alzheimer Disease; Anemia; Anemia, Sickle Cell; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Gastrinoma; Gastritis; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer Potassium-transporting ATPase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL

Alzheimer Disease; Anemia; Anemia, Sickle Cell; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Gastrinoma; Gastritis; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Approved EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER INJECTION; ORAL Brain Diseases; Brain Injuries; Dyspnea; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Pruritus; Small Cell Lung Carcinoma; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Syncope; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting Serotonin 3a (5-HT3a) receptor antagonist

Small molecule

Approved

EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER

INJECTION; ORAL

Brain Diseases; Brain Injuries; Dyspnea; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Pruritus; Small Cell Lung Carcinoma; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Syncope; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Serotonin 3a (5-HT3a) receptor antagonist


Small molecule Approved GASTROINTESTINAL; OTHER; RESPIRATORY INHALATION; NASAL; ORAL; RECTAL Cholangitis, Sclerosing; Anosmia; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Bronchiolitis Obliterans; Diarrhea; Esophageal Stenosis; Hepatitis, Autoimmune; Hypersensitivity; Inflammatory Bowel Diseases; Lung Neoplasms; Malnutrition; Melanoma; Multiple Myeloma; Nasal Polyps; Proctitis; Radiation Pneumonitis; Respiratory Distress Syndrome; Status Asthmaticus; Altitude Sickness; Bronchiolitis Obliterans Syndrome; Bronchopulmonary Dysplasia; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Eosinophilic Esophagitis; Graft vs Host Disease; Liver Cirrhosis, Biliary; Proctocolitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Snoring; Asthma; Bronchitis, Chronic; Colitis, Ulcerative; Crohn Disease; Emphysema; Esophageal Diseases; Glomerulonephritis, IGA; Lung Diseases, Obstructive; Nasal Obstruction; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal Glucocorticoid receptor agonist

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INHALATION; NASAL; ORAL; RECTAL

Cholangitis, Sclerosing; Anosmia; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Bronchiolitis Obliterans; Diarrhea; Esophageal Stenosis; Hepatitis, Autoimmune; Hypersensitivity; Inflammatory Bowel Diseases; Lung Neoplasms; Malnutrition; Melanoma; Multiple Myeloma; Nasal Polyps; Proctitis; Radiation Pneumonitis; Respiratory Distress Syndrome; Status Asthmaticus; Altitude Sickness; Bronchiolitis Obliterans Syndrome; Bronchopulmonary Dysplasia; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Eosinophilic Esophagitis; Graft vs Host Disease; Liver Cirrhosis, Biliary; Proctocolitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Snoring; Asthma; Bronchitis, Chronic; Colitis, Ulcerative; Crohn Disease; Emphysema; Esophageal Diseases; Glomerulonephritis, IGA; Lung Diseases, Obstructive; Nasal Obstruction; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

Glucocorticoid receptor agonist


Small molecule Approved GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer; Stomach Ulcer Potassium-transporting ATPase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Approved GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION; INTRAVENOUS Gram-Negative Bacterial Infections; Osteomyelitis; Pancreatitis; Respiratory Insufficiency; Appendicitis; Communicable Diseases; Hematologic Neoplasms; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Lung Diseases; Mental Disorders; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Urinary Bladder Neoplasms; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION; INTRAVENOUS

Gram-Negative Bacterial Infections; Osteomyelitis; Pancreatitis; Respiratory Insufficiency; Appendicitis; Communicable Diseases; Hematologic Neoplasms; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Lung Diseases; Mental Disorders; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Urinary Bladder Neoplasms; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections

Bacterial penicillin-binding protein inhibitor


Protein Approved GASTROINTESTINAL; OTHER INJECTION Dyspepsia; Pancreatitis, Chronic; Obesity; Pancreatitis; Schizophrenia; Autistic Disorder Secretin receptor agonist


Protein Approved GASTROINTESTINAL; OTHER INTRAVENOUS Autistic Disorder Secretin receptor agonist


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Constipation; Irritable Bowel Syndrome Serotonin 4 (5-HT4) receptor partial agonist


Small molecule Approved CANCER; GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting Neurokinin 1 receptor antagonist

Small molecule

Approved

CANCER; GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting

Neurokinin 1 receptor antagonist


Antibody Approved GASTROINTESTINAL INTRAVENOUS Astrocytoma; Brain Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Pancreatic Ductal; Precancerous Conditions; Adenocarcinoma; Adenocarcinoma of Lung; Anus Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Verrucous; Cholangiocarcinoma; Chordoma; Complex Regional Pain Syndromes; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Glioma; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Liver Neoplasms; Mouth Neoplasms; Multiple Myeloma; Neoplasm Metastasis; Neuralgia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Salivary Gland Neoplasms; Sarcoma; Skin Neoplasms; Tongue Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Esophageal Neoplasms; Lung Neoplasms; Nasopharyngeal Carcinoma; Pancreatic Neoplasms; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Neoplasms Epidermal growth factor receptor erbB1 inhibitor

Antibody

Approved

GASTROINTESTINAL

INTRAVENOUS

Astrocytoma; Brain Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Pancreatic Ductal; Precancerous Conditions; Adenocarcinoma; Adenocarcinoma of Lung; Anus Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Verrucous; Cholangiocarcinoma; Chordoma; Complex Regional Pain Syndromes; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Glioma; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Liver Neoplasms; Mouth Neoplasms; Multiple Myeloma; Neoplasm Metastasis; Neuralgia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Salivary Gland Neoplasms; Sarcoma; Skin Neoplasms; Tongue Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Esophageal Neoplasms; Lung Neoplasms; Nasopharyngeal Carcinoma; Pancreatic Neoplasms; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Neoplasms

Epidermal growth factor receptor erbB1 inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL HIV Infections; Chronic Pain; Constipation; Irritable Bowel Syndrome Chloride channel protein 2 opener


Small molecule Approved GASTROINTESTINAL ORAL Clostridium Infections; Diarrhea; Infections DNA-directed RNA polymerase inhibitor


Protein Approved GASTROINTESTINAL ORAL Liver Diseases; Thrombocytopenia; Hepatitis C; HIV Infections; Infections; Hepatitis C, Chronic; Virus Diseases Hepatitis C virus serine protease, NS3/NS4A inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER; UROLOGY AND KIDNEY ORAL Bone Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Cholangiocarcinoma; Digestive System Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Hemangiosarcoma; Liposarcoma; Macular Degeneration; Melanoma; Meningioma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neoplasms Discoidin domain-containing receptor 2 inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER; UROLOGY AND KIDNEY

ORAL

Bone Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Cholangiocarcinoma; Digestive System Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Hemangiosarcoma; Liposarcoma; Macular Degeneration; Melanoma; Meningioma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neoplasms

Discoidin domain-containing receptor 2 inhibitor


Protein Approved GASTROINTESTINAL; OTHER ORAL Adenoma; Colorectal Neoplasms; Constipation; Irritable Bowel Syndrome Heat-stable enterotoxin receptor agonist


Small molecule Approved GASTROINTESTINAL ORAL Breast Neoplasms; Irritable Bowel Syndrome; Diarrhea Anoctamin-1 blocker


Antibody Approved GASTROINTESTINAL INJECTION Diabetes Mellitus, Type 1; Inflammatory Bowel Diseases; Melanoma; Celiac Disease; Colitis; HIV Infections; Infections; Neoplasms; Salivary Gland Neoplasms; Pouchitis; Colitis, Ulcerative; Crohn Disease Integrin alpha-4/beta-7 inhibitor


Antibody Approved GASTROINTESTINAL; OTHER INJECTION Desmoplastic Small Round Cell Tumor; Glioma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Sarcoma, Synovial; Adenocarcinoma; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Glioblastoma; Head and Neck Neoplasms; Lung Neoplasms; Melanoma; Mesothelioma; Mesothelioma, Malignant; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Thymoma; Breast Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms; Stomach Neoplasms Vascular endothelial growth factor receptor 2 inhibitor

Antibody

Approved

GASTROINTESTINAL; OTHER

INJECTION

Desmoplastic Small Round Cell Tumor; Glioma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Sarcoma, Synovial; Adenocarcinoma; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Glioblastoma; Head and Neck Neoplasms; Lung Neoplasms; Melanoma; Mesothelioma; Mesothelioma, Malignant; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Thymoma; Breast Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms; Stomach Neoplasms

Vascular endothelial growth factor receptor 2 inhibitor


Combination Approved GASTROINTESTINAL; OTHER; RHEUMATOLOGY ORAL Unknown Unknown


Combination Approved GASTROINTESTINAL ORAL Unknown Unknown

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; GASTROINTESTINAL; OTHER

INJECTION; NASAL; ORAL

Fallopian Tube Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Mycosis Fungoides; Ovarian Neoplasms; Peritoneal Neoplasms; Pulmonary Alveolar Proteinosis; Sezary Syndrome; Arthralgia; Atherosclerosis; Autistic Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Depressive Disorder; Diabetic Neuropathies; Head and Neck Neoplasms; Heart Diseases; Heart Failure; HIV Infections; Lung Neoplasms; Lymphoma; Lymphoma, T-Cell, Peripheral; Mesothelioma; Myocardial Infarction; Myocardial Ischemia; Nasopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Vitamin B 12 Deficiency; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain Injuries; Low Back Pain; Pregnancy; Premature Ejaculation; Psoriasis; Psychotic Disorders; Anemia; Anemia, Iron-Deficiency; Diabetes Mellitus, Type 2; Folic Acid Deficiency; Kidney Failure, Chronic; Nasal Obstruction; Osteoporosis; Vitamin B Deficiency

Supplement


Combination Approved GASTROINTESTINAL INTRAVENOUS Unknown Unknown


Combination Approved GASTROINTESTINAL; OTHER CAPSULE; DELAYED REL PELLETS; ORAL Unknown Unknown