DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 43


Small molecule Approved OTHER; PEDIATRICS; RESPIRATORY DENTAL; INHALATION; INJECTION; INTRA-ARTICULAR; INTRAMUSCULAR; INTRAVITREAL; NASAL; SUSPENSION; TOPICAL Fibroma; Hearing Loss; Mucositis; Neuroma, Acoustic; Papilledema; Rotator Cuff Injuries; Tendon Entrapment; Alopecia Areata; Breast Neoplasms; Cataract; Complex Regional Pain Syndromes; Dermatitis, Atopic; Glaucoma; Hand Dermatoses; Humeral Fractures; Keloid; Lichen Planus; Pemphigoid, Benign Mucous Membrane; Psoriasis; Shoulder Pain; Ulnar Neuropathies; Uveal Melanoma; Uveomeningoencephalitic Syndrome; Vitiligo; Wet Macular Degeneration; Chalazion; Choroidal Neovascularization; Cough; Cystitis, Interstitial; Diabetic Retinopathy; Dupuytren Contracture; Eye Injuries; Lichen Planus, Oral; Macular Degeneration; Macular Edema; Optic Neuropathy, Ischemic; Osteoarthritis, Hip; Osteoarthritis, Knee; Otitis Media with Effusion; Pemphigus; Radiculopathy; Retinal Vein Occlusion; Rhinitis; Tendinopathy; Uveitis; Vitreoretinopathy, Proliferative; Anemia; Arthritis, Gouty; Arthritis, Rheumatoid; Asthma; Bursitis; Dermatitis; Multiple Sclerosis; Mycoses; Nasal Obstruction; Osteoarthritis; Pain; Rhinitis, Allergic, Seasonal; Serum Sickness; Skin Diseases; Tennis Elbow; Tenosynovitis; Tuberculosis, Pulmonary; Wounds and Injuries Glucocorticoid receptor agonist

Small molecule

Approved

OTHER; PEDIATRICS; RESPIRATORY

DENTAL; INHALATION; INJECTION; INTRA-ARTICULAR; INTRAMUSCULAR; INTRAVITREAL; NASAL; SUSPENSION; TOPICAL

Fibroma; Hearing Loss; Mucositis; Neuroma, Acoustic; Papilledema; Rotator Cuff Injuries; Tendon Entrapment; Alopecia Areata; Breast Neoplasms; Cataract; Complex Regional Pain Syndromes; Dermatitis, Atopic; Glaucoma; Hand Dermatoses; Humeral Fractures; Keloid; Lichen Planus; Pemphigoid, Benign Mucous Membrane; Psoriasis; Shoulder Pain; Ulnar Neuropathies; Uveal Melanoma; Uveomeningoencephalitic Syndrome; Vitiligo; Wet Macular Degeneration; Chalazion; Choroidal Neovascularization; Cough; Cystitis, Interstitial; Diabetic Retinopathy; Dupuytren Contracture; Eye Injuries; Lichen Planus, Oral; Macular Degeneration; Macular Edema; Optic Neuropathy, Ischemic; Osteoarthritis, Hip; Osteoarthritis, Knee; Otitis Media with Effusion; Pemphigus; Radiculopathy; Retinal Vein Occlusion; Rhinitis; Tendinopathy; Uveitis; Vitreoretinopathy, Proliferative; Anemia; Arthritis, Gouty; Arthritis, Rheumatoid; Asthma; Bursitis; Dermatitis; Multiple Sclerosis; Mycoses; Nasal Obstruction; Osteoarthritis; Pain; Rhinitis, Allergic, Seasonal; Serum Sickness; Skin Diseases; Tennis Elbow; Tenosynovitis; Tuberculosis, Pulmonary; Wounds and Injuries

Glucocorticoid receptor agonist


Small molecule Approved OTHER; RESPIRATORY INHALATION; OPHTHALMIC Bronchopulmonary Dysplasia; Diabetic Foot; Dry Eye Syndromes; Osteomyelitis; Renal Insufficiency, Chronic; Sinusitis; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation; Respiratory Tract Infections 70S ribosome inhibitor

Small molecule

Approved

OTHER; RESPIRATORY

INHALATION; OPHTHALMIC

Bronchopulmonary Dysplasia; Diabetic Foot; Dry Eye Syndromes; Osteomyelitis; Renal Insufficiency, Chronic; Sinusitis; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation; Respiratory Tract Infections

70S ribosome inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Hypersensitivity; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Common Cold; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Urticaria Histamine H1 receptor antagonist


Small molecule Approved OTHER; RESPIRATORY INHALATION Ciliary Motility Disorders; Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Tachypnea; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Abdominal Pain; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist

Small molecule

Approved

OTHER; RESPIRATORY

INHALATION

Ciliary Motility Disorders; Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Tachypnea; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Abdominal Pain; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive

Beta-2 adrenergic receptor agonist


Small molecule Approved OTHER; RESPIRATORY INHALATION; INJECTION Carcinoma, Non-Small-Cell Lung; Osteomyelitis; Renal Insufficiency; Gonorrhea; Gram-Negative Bacterial Infections; Enterobacteriaceae Infections; Skin Diseases; Bacterial Infections; Cystic Fibrosis; Infections; Intraabdominal Infections; Pneumonia; Pyelonephritis; Sepsis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

OTHER; RESPIRATORY

INHALATION; INJECTION

Carcinoma, Non-Small-Cell Lung; Osteomyelitis; Renal Insufficiency; Gonorrhea; Gram-Negative Bacterial Infections; Enterobacteriaceae Infections; Skin Diseases; Bacterial Infections; Cystic Fibrosis; Infections; Intraabdominal Infections; Pneumonia; Pyelonephritis; Sepsis; Urinary Tract Infections

Bacterial penicillin-binding protein inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER; RESPIRATORY INJECTION; ORAL; OTIC Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections Bacterial DNA gyrase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INJECTION; ORAL; OTIC

Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections

Bacterial DNA gyrase inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Osteomyelitis; Bronchitis, Chronic; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Sinusitis; Tonsillitis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Osteomyelitis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Disorders of Excessive Somnolence; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis Bacterial 70S ribosome inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; RESPIRATORY

ORAL

Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Osteomyelitis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Disorders of Excessive Somnolence; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis

Bacterial 70S ribosome inhibitor


Small molecule Approved CANCER; OTHER; RESPIRATORY INJECTION; IV (INFUSION) Anus Neoplasms; Brain Neoplasms; Carcinoid Tumor; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Verrucous; Coronary Restenosis; Glioblastoma; Gliosarcoma; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Mesothelioma; Neoplasms, Cystic, Mucinous, and Serous; Rectal Neoplasms; Thyroid Carcinoma, Anaplastic; Vaginal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Neoplasms; Arthritis, Rheumatoid; Bone Neoplasms; Breast Carcinoma In Situ; Carcinoma, Ductal; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Central Nervous System Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Constriction, Pathologic; Cystadenoma, Serous; Digestive System Diseases; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Hypopharyngeal Neoplasms; Keratosis, Actinic; Kidney Neoplasms; Leukemia; Lymphoma; Mouth Neoplasms; Multiple Myeloma; Neoplasms, Complex and Mixed; Neoplasms, Germ Cell and Embryonal; Oropharyngeal Neoplasms; Penile Neoplasms; Peripheral Vascular Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Psoriasis; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Thymoma; Uterine Cervical Dysplasia; Uveal Melanoma; Vulvar Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anemia; Biliary Tract Neoplasms; Breast Neoplasms, Male; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Head and Neck Neoplasms; HIV Infections; Hypersensitivity; Inflammatory Breast Neoplasms; Ischemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Pain; Paraganglioma; Peripheral Arterial Disease; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Sex Cord-Gonadal Stromal Tumors; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Sarcoma, Kaposi Tubulin inhibitor

Small molecule

Approved

CANCER; OTHER; RESPIRATORY

INJECTION; IV (INFUSION)

Anus Neoplasms; Brain Neoplasms; Carcinoid Tumor; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Verrucous; Coronary Restenosis; Glioblastoma; Gliosarcoma; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Mesothelioma; Neoplasms, Cystic, Mucinous, and Serous; Rectal Neoplasms; Thyroid Carcinoma, Anaplastic; Vaginal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Neoplasms; Arthritis, Rheumatoid; Bone Neoplasms; Breast Carcinoma In Situ; Carcinoma, Ductal; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Central Nervous System Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Constriction, Pathologic; Cystadenoma, Serous; Digestive System Diseases; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Hypopharyngeal Neoplasms; Keratosis, Actinic; Kidney Neoplasms; Leukemia; Lymphoma; Mouth Neoplasms; Multiple Myeloma; Neoplasms, Complex and Mixed; Neoplasms, Germ Cell and Embryonal; Oropharyngeal Neoplasms; Penile Neoplasms; Peripheral Vascular Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Psoriasis; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Thymoma; Uterine Cervical Dysplasia; Uveal Melanoma; Vulvar Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anemia; Biliary Tract Neoplasms; Breast Neoplasms, Male; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Head and Neck Neoplasms; HIV Infections; Hypersensitivity; Inflammatory Breast Neoplasms; Ischemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Pain; Paraganglioma; Peripheral Arterial Disease; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Sex Cord-Gonadal Stromal Tumors; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Sarcoma, Kaposi

Tubulin inhibitor


Enzyme Approved RESPIRATORY UNKNOWN Cough; Dry Eye Syndromes; Graft vs Host Disease; Head and Neck Neoplasms; Pleural Effusion; Sjogren's Syndrome; Asthma; Hypoxia; Infections; Ischemic Stroke; Empyema; Empyema, Pleural; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sinusitis; Wounds and Injuries; Cystic Fibrosis DNA hydrolytic enzyme


Small molecule Approved GASTROINTESTINAL; OTHER; RESPIRATORY INHALATION; NASAL; ORAL; RECTAL Cholangitis, Sclerosing; Anosmia; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Bronchiolitis Obliterans; Diarrhea; Esophageal Stenosis; Hepatitis, Autoimmune; Hypersensitivity; Inflammatory Bowel Diseases; Lung Neoplasms; Malnutrition; Melanoma; Multiple Myeloma; Nasal Polyps; Proctitis; Radiation Pneumonitis; Respiratory Distress Syndrome; Status Asthmaticus; Altitude Sickness; Bronchiolitis Obliterans Syndrome; Bronchopulmonary Dysplasia; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Eosinophilic Esophagitis; Graft vs Host Disease; Liver Cirrhosis, Biliary; Proctocolitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Snoring; Asthma; Bronchitis, Chronic; Colitis, Ulcerative; Crohn Disease; Emphysema; Esophageal Diseases; Glomerulonephritis, IGA; Lung Diseases, Obstructive; Nasal Obstruction; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal Glucocorticoid receptor agonist

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INHALATION; NASAL; ORAL; RECTAL

Cholangitis, Sclerosing; Anosmia; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Bronchiolitis Obliterans; Diarrhea; Esophageal Stenosis; Hepatitis, Autoimmune; Hypersensitivity; Inflammatory Bowel Diseases; Lung Neoplasms; Malnutrition; Melanoma; Multiple Myeloma; Nasal Polyps; Proctitis; Radiation Pneumonitis; Respiratory Distress Syndrome; Status Asthmaticus; Altitude Sickness; Bronchiolitis Obliterans Syndrome; Bronchopulmonary Dysplasia; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Eosinophilic Esophagitis; Graft vs Host Disease; Liver Cirrhosis, Biliary; Proctocolitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Snoring; Asthma; Bronchitis, Chronic; Colitis, Ulcerative; Crohn Disease; Emphysema; Esophageal Diseases; Glomerulonephritis, IGA; Lung Diseases, Obstructive; Nasal Obstruction; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

Glucocorticoid receptor agonist


Small molecule Approved RESPIRATORY ORAL Osteomyelitis; Bacterial Infections Bacterial DNA gyrase inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Breast Neoplasms; Hypersensitivity; Ovarian Neoplasms; Asthma; Lung Diseases, Obstructive Cysteinyl leukotriene receptor 1 antagonist


Small molecule Approved OTHER; RESPIRATORY ORAL Anemia, Sickle Cell; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Acne Vulgaris; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Tobacco Use Disorder; Pulmonary Disease, Chronic Obstructive; Asthma Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved ENT; OTHER; PHARMACOLOGY; RESPIRATORY ORAL Appendicitis; Osteomyelitis; Mastitis; Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Tonsillitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER; RESPIRATORY INTRAPLEURAL Carcinoma, Non-Small-Cell Lung; Osteoarthritis, Hip; Osteoarthritis, Knee; Radius Fractures; Pleural Effusion Unknown


Small molecule Approved RESPIRATORY ORAL Osteomyelitis; HIV Infections; Tuberculosis, Pulmonary; Tuberculosis Bacterial DNA-directed RNA polymerase inhibitor


Antibody Approved OTHER; RESPIRATORY UNKNOWN Hernias, Diaphragmatic, Congenital; Bronchopulmonary Dysplasia; Respiratory Syncytial Virus Infections; Respiratory Tract Diseases Fusion glycoprotein F0 inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Romano-Ward Syndrome; Heart Failure; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter HERG blocker


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Eczema; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Pruritus; Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Urticaria Histamine H1 receptor antagonist

Small molecule

Approved

IMMUNE SYSTEM; OTHER; RESPIRATORY

ORAL

Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Eczema; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Pruritus; Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Urticaria

Histamine H1 receptor antagonist


Small molecule Approved OTHER; RESPIRATORY INHALATION Lung Neoplasms; Tobacco Use Disorder; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist


Small molecule Approved CARDIOVASCULAR; OTHER; RESPIRATORY INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS Diabetes Mellitus, Type 1; Diabetic Foot; Raynaud Disease; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis Prostanoid IP receptor agonist

Small molecule

Approved

CARDIOVASCULAR; OTHER; RESPIRATORY

INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS

Diabetes Mellitus, Type 1; Diabetic Foot; Raynaud Disease; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis

Prostanoid IP receptor agonist


Enzyme Approved RESPIRATORY UNKNOWN Glycogen Storage Disease Type III; Mucopolysaccharidoses; Mucopolysaccharidosis I Dermatan sulfate hydrolytic enzyme


Antibody Approved RESPIRATORY UNKNOWN Colonic Neoplasms; Dermatitis, Atopic; Drug Hypersensitivity; Job Syndrome; Lupus Erythematosus, Systemic; Bronchitis; Chronic Inducible Urticaria; Cold Urticaria; Eosinophilic Esophagitis; Food Hypersensitivity; Gastroenteritis; Hypersensitivity; Immune System Diseases; Milk Hypersensitivity; Nephritis, Interstitial; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Angioedema; Chronic Urticaria; Cystitis, Interstitial; Peanut Hypersensitivity; Rhinitis, Allergic, Seasonal; Sinusitis; Asthma; Lung Diseases, Obstructive; Rhinitis; Urticaria Ig epsilon chain C region inhibitor

Antibody

Approved

RESPIRATORY

UNKNOWN

Colonic Neoplasms; Dermatitis, Atopic; Drug Hypersensitivity; Job Syndrome; Lupus Erythematosus, Systemic; Bronchitis; Chronic Inducible Urticaria; Cold Urticaria; Eosinophilic Esophagitis; Food Hypersensitivity; Gastroenteritis; Hypersensitivity; Immune System Diseases; Milk Hypersensitivity; Nephritis, Interstitial; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Angioedema; Chronic Urticaria; Cystitis, Interstitial; Peanut Hypersensitivity; Rhinitis, Allergic, Seasonal; Sinusitis; Asthma; Lung Diseases, Obstructive; Rhinitis; Urticaria

Ig epsilon chain C region inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY ORAL Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension Phosphodiesterase 5A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY

ORAL

Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension

Phosphodiesterase 5A inhibitor


Small molecule Approved OTHER; RESPIRATORY INHALATION Cystic Fibrosis; Neoplasms; Spinal Cord Injuries; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive Muscarinic acetylcholine receptor M3 antagonist


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Asthma; Maxillary Sinusitis; Otitis Media; Otitis Media, Suppurative; Scrub Typhus; Bacterial Infections; Bronchitis, Chronic; Community-Acquired Infections; Infections; Pharyngitis; Pneumonia; Pneumonia, Bacterial; Sinusitis; Tonsillitis Bacterial 70S ribosome inhibitor


Small molecule Approved OTHER; PEDIATRICS; RESPIRATORY INHALATION; NASAL Pulmonary Disease, Chronic Obstructive; Chronic Disease; Hypersensitivity; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal Glucocorticoid receptor agonist


Small molecule Approved CARDIOVASCULAR; OTHER; RESPIRATORY ORAL Anemia, Sickle Cell; Altitude Sickness; Asthma; Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Vascular Diseases; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension Endothelin receptor, ET-A/ET-B antagonist


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY INJECTION Renal Insufficiency, Chronic; Gram-Positive Bacterial Infections; Infections; Bacteremia; Bacterial Infections; Pneumonia, Bacterial; Staphylococcal Skin Infections Unknown


Small molecule Approved OTHER; RESPIRATORY INTRAVENOUS Kidney Diseases; Systemic Inflammatory Response Syndrome; Sepsis; Urinary Tract Infections; Infections; Pneumonia, Bacterial; Bacterial Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved RESPIRATORY ORAL Glioblastoma; Heart Failure; Idiopathic Pulmonary Fibrosis; Hernias, Diaphragmatic, Congenital; Pulmonary Embolism; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary Endothelin receptor, ET-A/ET-B antagonist

Small molecule

Approved

CANCER; OTHER; RESPIRATORY

ORAL

Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Bile Duct Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Gallbladder Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Uveal Melanoma; Adenocarcinoma of Lung; Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms

ALK tyrosine kinase receptor inhibitor

Small molecule

Approved

RESPIRATORY

ORAL

Multiple Sclerosis; Acute Lung Injury; Alveolitis, Extrinsic Allergic; Bronchiolitis Obliterans; Burns; Carcinoma, Squamous Cell; Cardiomyopathy, Hypertrophic; Glomerulosclerosis, Focal Segmental; Heart Failure; Leiomyoma; Lung Diseases, Interstitial; Lung Neoplasms; Nephrotic Syndrome; Neurofibromatosis 1; Pancreatitis; Proteinuria; Pulmonary Fibrosis; Radiation Pneumonitis; Renal Insufficiency; Renal Insufficiency, Chronic; Scleroderma, Systemic; Diabetic Foot; Keloid; Pneumoconiosis; Pneumonia; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Immune System Diseases; Lung Diseases; Respiratory Tract Diseases

Unknown


Small molecule Approved RESPIRATORY ORAL Tuberculosis; Tuberculosis, Multidrug-Resistant ATP synthase inhibitor