AMINOCAPROIC ACID

Search structure
Trade Names:
Synonyms:
Status: Approved (1964)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: B02AA01
UNII: U6F3787206

Structure
InChI Key SLXKOJJOQWFEFD-UHFFFAOYSA-N
Smile NCCCCCC(=O)O
InChI
InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H13NO2
Molecular Weight 131.18
AlogP 0.59
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 5.0
Polar Surface Area 63.32
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 9.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Plasminogen inhibitor DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily
- 40000 9000 - -

Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Inflammation 2 D007249 ClinicalTrials
Craniosynostoses 1 D003398 ClinicalTrials
Aortic Diseases 0 D001018 ClinicalTrials
Rosacea 0 D012393 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Vascular disorders
22.92
Nervous system disorders
20.83
General disorders and administration site conditions
14.58
Respiratory, thoracic and mediastinal disorders
10.42
Psychiatric disorders
8.33
Injury, poisoning and procedural complications
6.25
Eye disorders
4.17
Immune system disorders
4.17
Investigations
4.17
Skin and subcutaneous tissue disorders
4.17

Cross References

Resources Reference
CAS NUMBER 60-32-2
ChEBI 57826
ChEMBL CHEMBL1046
DrugBank DB00513
DrugCentral 163
EPA CompTox DTXSID0020070
FDA SRS U6F3787206
Human Metabolome Database HMDB0001901
Guide to Pharmacology 6574
KEGG C02378
PDB ACA
PharmGKB PA164774947
PubChem 564
SureChEMBL SCHEMBL15293
ZINC ZINC000001529425
CONTENTS