AMINOSALICYLATE SODIUM

Search structure


Trade Names:	PARASAL SODIUM P.A.S. SODIUM SODIUM AMINOSALICYLATE SODIUM P.A.S. TEEBACIN
Synonyms:	Aminacyl Aminosalicylate sodium Aminosalyle sodium Nemasol sodium NSC-755862 Para-aminosodium salicylate Paramisan sodium Parasal sodium Pasalon Pas-c P.a.s. sodium Sodium aminosalicylate Sodium Aminosalicylate Sodium p.a.s. Teebacin
Status:	Approved (1950)
Entry Type:	Small molecule
Molecule Category:	Salt
UNII:	S38B9W6AXW

Structure


InChI Key	GMUQJDAYXZXBOT-UHFFFAOYSA-M
Smile	Nc1ccc(C(=O)[O-])c(O)c1.O.O.[Na+]
InChI	InChI=1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C7H10NNaO5
Molecular Weight	211.15
AlogP	0.67
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	1.0
Polar Surface Area	83.55
Molecular species	ACID
Aromatic Rings	1.0
Heavy Atoms	11.0

Pharmacology

Action	Mechanism of Action	Reference
INHIBITOR	Dihydrofolate reductase inhibitor	PubMed PubMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	76

Related Entries

Mixture

Cross References

Resources	Reference
ChEMBL	CHEMBL2096646
EPA CompTox	DTXSID5036638
FDA SRS	S38B9W6AXW
PubChem	16211148
SureChEMBL	SCHEMBL84166

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