Trade Names:
Synonyms:
Status: Approved (2017)
Entry Type: Antibody
Molecule Category: UNKNOWN
ATC: R03DX10
UNII: 71492GE1FX

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Interleukin-5 receptor subunit alpha inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Asthma 4 D001249 FDA
Hypereosinophilic Syndrome 3 D017681 ClinicalTrials
Nasal Polyps 3 D009298 ClinicalTrials
Pemphigoid, Bullous 3 D010391 ClinicalTrials
Eosinophilic Esophagitis 3 D057765 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 3 D029424 ClinicalTrials
Sinusitis 2 D012852 ClinicalTrials
Dermatitis, Atopic 2 D003876 ClinicalTrials
Urticaria 2 D014581 ClinicalTrials
Hematologic Diseases 2 D006402 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Respiratory, thoracic and mediastinal disorders
17.69
General disorders and administration site conditions
15.28
Immune system disorders
8.78
Nervous system disorders
8.19
Skin and subcutaneous tissue disorders
7.74
Cardiac disorders
5.92
Injury, poisoning and procedural complications
5.78
Gastrointestinal disorders
5.36
Musculoskeletal and connective tissue disorders
4.82
Vascular disorders
4.38
Infections and infestations
4.22
Psychiatric disorders
2.81
Investigations
2.66

Cross References

Resources Reference
CAS NUMBER 1044511-01-4
ChEMBL CHEMBL1742991
FDA SRS 71492GE1FX
Guide to Pharmacology 7674