BISOPROLOL FUMARATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1992)
Entry Type: Small molecule
Molecule Category: Parent
UNII: UR59KN573L

Structure
InChI Key RZPZLFIUFMNCLY-WLHGVMLRSA-N
Smile CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.O=C(O)/C=C/C(=O)O
InChI
InChI=1S/C18H31NO4.C4H4O4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

Physicochemical Descriptors

Property Name Value
Molecular Formula C40H66N2O12
Molecular Weight 766.97
AlogP 2.37
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 12.0
Polar Surface Area 59.95
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Beta-1 adrenergic receptor antagonist DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Muscular Dystrophy, Duchenne 2 D020388 ClinicalTrials
Lecithin Cholesterol Acyltransferase Deficiency 1 D007863 ClinicalTrials

Related Entries

MCS

Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Cardiac disorders
16.17
Nervous system disorders
12.41
General disorders and administration site conditions
11.09
Vascular disorders
10.05
Respiratory, thoracic and mediastinal disorders
6.49
Psychiatric disorders
5.88
Injury, poisoning and procedural complications
5.78
Investigations
4.59
Skin and subcutaneous tissue disorders
4.58
Gastrointestinal disorders
3.87
Musculoskeletal and connective tissue disorders
3.32
Metabolism and nutrition disorders
2.89
Renal and urinary disorders
2.43
Immune system disorders
2.05

Cross References

Resources Reference
ChEBI 3128
ChEMBL CHEMBL1472989
EPA CompTox DTXSID1045794
FDA SRS UR59KN573L
PubChem 5281064
SureChEMBL SCHEMBL41418
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