Trade Names:
Synonyms:
Status: Approved (2014)
Entry Type: Antibody
Molecule Category: UNKNOWN
ATC: L01XC19
UNII: 4FR53SIF3A

Pharmacology

Action Mechanism of Action Reference
CROSS-LINKING AGENT B-lymphocyte antigen CD19 cross-linking agent FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 D054198 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 D054198 ClinicalTrials
Lymphoma, Non-Hodgkin 2 D008228 ClinicalTrials
Leukemia, Biphenotypic, Acute 2 D015456 ClinicalTrials
Leukemia, Biphenotypic, Acute 2 D015456 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 2 D016403 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 1 D015451 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Leukemia 1 D007938 ClinicalTrials
Multiple Myeloma 0 D009101 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
16.27
Nervous system disorders
13.53
Injury, poisoning and procedural complications
10.0
Blood and lymphatic system disorders
7.95
Investigations
7.79
Infections and infestations
4.63
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
4.59
Vascular disorders
4.42
Psychiatric disorders
4.35
Immune system disorders
3.84
Respiratory, thoracic and mediastinal disorders
3.55
Gastrointestinal disorders
3.48
Musculoskeletal and connective tissue disorders
2.95
Cardiac disorders
2.42
Metabolism and nutrition disorders
2.33
Skin and subcutaneous tissue disorders
2.09

Cross References

Resources Reference
CAS NUMBER 853426-35-4
ChEMBL CHEMBL1742992
FDA SRS 4FR53SIF3A
Guide to Pharmacology 7384