BRIVARACETAM

Search structure
Trade Names:
Synonyms:
Status: Approved (2016)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: N03AX23
UNII: U863JGG2IA

Structure
InChI Key MSYKRHVOOPPJKU-BDAKNGLRSA-N
Smile CCC[C@@H]1CC(=O)N([C@@H](CC)C(N)=O)C1
InChI
InChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H20N2O2
Molecular Weight 212.29
AlogP 0.9
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 63.4
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 15.0

Pharmacology

Action Mechanism of Action Reference
MODULATOR Synaptic vesicle glycoprotein 2A modulator FDA PubMed
Primary Target
synaptic vesicle glycoprotein 2A

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Epilepsy 4 D004827 ClinicalTrials
Unverricht-Lundborg Syndrome 3 D020194 ClinicalTrials
Neuralgia, Postherpetic 2 D051474 ClinicalTrials
Spinal Cord Injuries 1 D013119 ClinicalTrials

Related Entries

MCS

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Nervous system disorders
26.19
Psychiatric disorders
14.64
Injury, poisoning and procedural complications
13.58
General disorders and administration site conditions
10.5
Gastrointestinal disorders
6.34
Respiratory, thoracic and mediastinal disorders
4.02
Vascular disorders
3.46
Skin and subcutaneous tissue disorders
3.13
Cardiac disorders
2.75
Investigations
2.38
Musculoskeletal and connective tissue disorders
2.2

Cross References

Resources Reference
CAS NUMBER 357336-20-0
ChEBI 133013
ChEMBL CHEMBL607400
DrugBank DB05541
DrugCentral 5068
FDA SRS U863JGG2IA
Guide to Pharmacology 9041
PharmGKB PA166153491
PubChem 9837243
SureChEMBL SCHEMBL122081
ZINC ZINC000003979899
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