CHLORPROPAMIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1958)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: A10BB02
UNII: WTM2C3IL2X

Structure
InChI Key RKWGIWYCVPQPMF-UHFFFAOYSA-N
Smile CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI
InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H13ClN2O3S
Molecular Weight 276.75
AlogP 1.74
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 75.27
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 17.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sulfonylurea receptor 1, Kir6.2 blocker PubMed PubMed Wikipedia FDA
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Oxidoreductase
- - - - 0-0
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 102
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters
- - - 39500 -

Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

MCS

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Injury, poisoning and procedural complications
23.53
Cardiac disorders
11.76
Endocrine disorders
11.76
Metabolism and nutrition disorders
11.76
Nervous system disorders
11.76
Psychiatric disorders
11.76
Immune system disorders
5.88
Musculoskeletal and connective tissue disorders
5.88
Vascular disorders
5.88

Cross References

Resources Reference
CAS NUMBER 94-20-2
ChEBI 3650
ChEMBL CHEMBL498
DrugBank DB00672
DrugCentral 622
EPA CompTox DTXSID9020322
FDA SRS WTM2C3IL2X
Human Metabolome Database HMDB0014810
Guide to Pharmacology 6801
KEGG D00271
PharmGKB PA448966
PubChem 2727
SureChEMBL SCHEMBL23947
ZINC ZINC000001530599
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