CLINDAMYCIN PALMITATE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1986)
Entry Type: Small molecule
Molecule Category: Salt Prodrug
UNII: VN9A8JM7M7
Parent Compound: CLINDAMYCIN

Structure
InChI Key GTNDZRUWKHDICY-DJHAJVGHSA-N
Smile CCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](O)[C@@H](O)[C@@H]([C@H](NC(=O)[C@@H]2C[C@@H](CCC)CN2C)[C@H](C)Cl)O[C@@H]1SC.Cl
InChI
InChI=1S/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C34H64Cl2N2O6S
Molecular Weight 699.87
AlogP 6.42
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 22.0
Polar Surface Area 108.33
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 44.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial 70S ribosome inhibitor PubMed DailyMed Wikipedia Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
16.71
Injury, poisoning and procedural complications
13.83
Gastrointestinal disorders
11.82
Skin and subcutaneous tissue disorders
11.24
Infections and infestations
10.66
Product issues
7.78
Immune system disorders
6.05
Cardiac disorders
3.75
Blood and lymphatic system disorders
3.46
Nervous system disorders
3.17
Vascular disorders
2.88

Cross References

Resources Reference
ChEBI 34647
ChEMBL CHEMBL1200632
EPA CompTox DTXSID3048734
FDA SRS VN9A8JM7M7
PubChem 16052038
SureChEMBL SCHEMBL41416
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