CYCLOPENTOLATE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1974)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 6D6X07D6BN
Parent Compound: CYCLOPENTOLATE

Structure
InChI Key RHKZVMUBMXGOLL-UHFFFAOYSA-N
Smile CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1.Cl
InChI
InChI=1S/C17H25NO3.ClH/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17;/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H26ClNO3
Molecular Weight 327.85
AlogP 2.18
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 6.0
Polar Surface Area 49.77
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Muscarinic acetylcholine receptor M3 antagonist ISBN PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 100

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Parent
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Nervous system disorders
25.76
Psychiatric disorders
13.91
Eye disorders
13.66
General disorders and administration site conditions
7.98
Cardiac disorders
5.8
Vascular disorders
5.08
Gastrointestinal disorders
4.96
Respiratory, thoracic and mediastinal disorders
4.35
Skin and subcutaneous tissue disorders
3.99
Injury, poisoning and procedural complications
3.87
Immune system disorders
2.66

Cross References

Resources Reference
ChEBI 4024
ChEMBL CHEMBL1200473
EPA CompTox DTXSID9045390
FDA SRS 6D6X07D6BN
Guide to Pharmacology 7153
KEGG C06932
PubChem 22162
SureChEMBL SCHEMBL24612
ZINC ZINC00155531
CONTENTS