| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1999) |
| Entry Type: | Protein |
| Molecule Category: | UNKNOWN |
| ATC: | L01XX29 |
| UNII: | 25E79B5CTM |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Elongation factor 2 inhibitor |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Lymphoma | 3 | D008223 | ClinicalTrials |
| Lymphoma, T-Cell, Peripheral | 3 | D016411 | ClinicalTrials |
| Leukemia, Lymphocytic, Chronic, B-Cell | 2 | D015451 | ClinicalTrials |
| Leukemia, Myeloid, Acute | 2 | D015470 | ClinicalTrials |
| Leukemia | 2 | D007938 | ClinicalTrials |
| Lymphoma, Non-Hodgkin | 2 | D008228 | ClinicalTrials |
| Ovarian Neoplasms | 2 | D010051 | ClinicalTrials |
| Melanoma | 2 | D008545 | ClinicalTrials |
| Pancreatic Neoplasms | 2 | D010190 | ClinicalTrials |
| Leukemia, Biphenotypic, Acute | 2 | D015456 | ClinicalTrials |
| Peritoneal Neoplasms | 2 | D010534 | ClinicalTrials |
| Fallopian Tube Neoplasms | 2 | D005185 | ClinicalTrials |
| Ovarian Neoplasms | 2 | D010051 | ClinicalTrials |
| Graft vs Host Disease | 2 | D006086 | ClinicalTrials |
| Melanoma | 2 | D008545 | ClinicalTrials |
| Fallopian Tube Neoplasms | 2 | D005185 | ClinicalTrials |
| Breast Neoplasms, Male | 1 | D018567 | ClinicalTrials |
| Carcinoma, Endometrioid | 1 | D018269 | ClinicalTrials |
| Multiple Myeloma | 1 | D009101 | ClinicalTrials |
| Cystadenoma, Serous | 1 | D018293 | ClinicalTrials |
| Kidney Neoplasms | 1 | D007680 | ClinicalTrials |
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 173146-27-5 |
| ChEMBL | CHEMBL1201550 |
| FDA SRS | 25E79B5CTM |
| Guide to Pharmacology | 7044 |
CONTENTS