EDROPHONIUM CHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1951)
Entry Type: Small molecule
Molecule Category: Salt
UNII: QO611KSM5P

Structure
InChI Key BXKDSDJJOVIHMX-UHFFFAOYSA-N
Smile CC[N+](C)(C)c1cccc(O)c1.[Cl-]
InChI
InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H16ClNO
Molecular Weight 201.7
AlogP 1.98
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 20.23
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 12.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Acetylcholinesterase inhibitor DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 200-5170 - 200-4800 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 79

Related Entries

Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Nervous system disorders
36.36
Eye disorders
18.18
Injury, poisoning and procedural complications
18.18
Cardiac disorders
9.09
Gastrointestinal disorders
9.09
Psychiatric disorders
9.09

Cross References

Resources Reference
ChEBI 4759
ChEMBL CHEMBL1128
EPA CompTox DTXSID1022978
FDA SRS QO611KSM5P
PubChem 8307
SureChEMBL SCHEMBL34789
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