ETANERCEPT

Search structure
Trade Names:
Synonyms:
SB4
Status: Approved (1998)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: L04AB01
UNII: OP401G7OJC

Pharmacology

Action Mechanism of Action Reference
INHIBITOR TNF-alpha inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Cachexia 3 D002100 ClinicalTrials
Inflammation 3 D007249 ClinicalTrials
Stevens-Johnson Syndrome 3 D013262 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Polymyalgia Rheumatica 3 D011111 ClinicalTrials
Anorexia 3 D000855 ClinicalTrials
Diabetes Mellitus, Type 1 3 D003922 ClinicalTrials
Arthritis 3 D001168 ClinicalTrials
Synovitis 2 D013585 ClinicalTrials
Pulmonary Fibrosis 2 D011658 ClinicalTrials
Stomatitis 2 D013280 ClinicalTrials
Lupus Erythematosus, Cutaneous 2 D008178 ClinicalTrials
Tinnitus 2 D014012 ClinicalTrials
Chronic Urticaria 2 D000080223 ClinicalTrials
Dermatomyositis 2 D003882 ClinicalTrials
Renal Insufficiency, Chronic 2 D051436 ClinicalTrials
Leukemia 2 D007938 ClinicalTrials
Reperfusion Injury 2 D015427 ClinicalTrials
Mucocutaneous Lymph Node Syndrome 2 D009080 ClinicalTrials
Lichen Planus 2 D008010 ClinicalTrials
Hidradenitis Suppurativa 2 D017497 ClinicalTrials
Metabolic Syndrome 2 D024821 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 2 D029424 ClinicalTrials
Sjogren's Syndrome 2 D012859 ClinicalTrials
Vitiligo 2 D014820 ClinicalTrials
Pemphigus 2 D010392 ClinicalTrials
Temporomandibular Joint Disorders 2 D013705 ClinicalTrials
Granulomatosis with Polyangiitis 2 D014890 ClinicalTrials
Lupus Nephritis 2 D008181 ClinicalTrials
Histiocytosis 2 D015614 ClinicalTrials
Radiculopathy 2 D011843 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Alzheimer Disease 2 D000544 ClinicalTrials
Asthma 2 D001249 ClinicalTrials
Immunoglobulin Light-chain Amyloidosis 2 D000075363 ClinicalTrials
Acquired Hyperostosis Syndrome 2 D020083 ClinicalTrials
Myelodysplastic Syndromes 1 D009190 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 1 D015451 ClinicalTrials
Fanconi Anemia 1 D005199 ClinicalTrials
Sciatica 1 D012585 ClinicalTrials
Persian Gulf Syndrome 1 D018923 ClinicalTrials
HIV Infections 1 D015658 ClinicalTrials
Myositis, Inclusion Body 1 D018979 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 1 D064129 ClinicalTrials
Subarachnoid Hemorrhage 1 D013345 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
21.74
Injury, poisoning and procedural complications
15.22
Musculoskeletal and connective tissue disorders
11.28
Skin and subcutaneous tissue disorders
10.18
Respiratory, thoracic and mediastinal disorders
6.05
Infections and infestations
5.45
Nervous system disorders
5.18
Immune system disorders
4.34
Gastrointestinal disorders
3.67
Vascular disorders
3.21
Psychiatric disorders
2.02

Cross References

Resources Reference
CAS NUMBER 185243-69-0
ChEMBL CHEMBL1201572
FDA SRS OP401G7OJC
Guide to Pharmacology 6789
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