ETHOXZOLAMIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1982)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: Z52H4811WX

Structure
InChI Key OUZWUKMCLIBBOG-UHFFFAOYSA-N
Smile CCOc1ccc2nc(S(N)(=O)=O)sc2c1
InChI
InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H10N2O3S2
Molecular Weight 258.32
AlogP 1.34
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 82.28
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 16.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Carbonic anhydrase inhibitor PubMed
Primary Target
carbonic anhydrase 14
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Lyase
- 0-5 1-1 1-8000 74
Enzyme
- 0-5 1-1 1-8000 74

Cross References

Resources Reference
CAS NUMBER 452-35-7
ChEBI 101096
ChEMBL CHEMBL18
DrugBank DB00311
DrugCentral 1089
EPA CompTox DTXSID1023021
FDA SRS Z52H4811WX
Human Metabolome Database HMDB0014456
Guide to Pharmacology 6814
KEGG D02441
PDB EZL
PharmGKB PA164754743
PubChem 3295
SureChEMBL SCHEMBL63941
ZINC ZINC000000056721
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