FILGRASTIM

Search structure
Trade Names:
Synonyms:
Status: Approved (1991)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: L03AA02
UNII: PVI5M0M1GW

Pharmacology

Action Mechanism of Action Reference
AGONIST Granulocyte colony stimulating factor receptor agonist PubMed PubMed DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Neoplasms 4 D009369 ClinicalTrials
Neoplasms 4 D009369 ClinicalTrials
Multiple Myeloma 3 D009101 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Myelodysplastic Syndromes 3 D009190 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Sarcoma 3 D012509 ClinicalTrials
Liver Cirrhosis 3 D008103 ClinicalTrials
Leukemia 3 D007938 ClinicalTrials
Chagas Cardiomyopathy 3 D002598 ClinicalTrials
Leukemia, Myeloid, Acute 3 D015470 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 D054198 ClinicalTrials
Lymphoma, Follicular 3 D008224 ClinicalTrials
Lymphoma, Non-Hodgkin 3 D008228 ClinicalTrials
Hepatitis, Alcoholic 3 D006519 ClinicalTrials
Retinoblastoma 3 D012175 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 3 D015451 ClinicalTrials
Leukemia, Monocytic, Acute 3 D007948 ClinicalTrials
Leukemia, Myelomonocytic, Acute 3 D015479 ClinicalTrials
Urinary Bladder Neoplasms 3 D001749 ClinicalTrials
Burkitt Lymphoma 3 D002051 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 3 D016403 ClinicalTrials
Neoplasms, Germ Cell and Embryonal 3 D009373 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Neuroblastoma 3 D009447 ClinicalTrials
Scleroderma, Systemic 3 D012595 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Liver Diseases 3 D008107 ClinicalTrials
Rhabdomyosarcoma 3 D012208 ClinicalTrials
Medulloblastoma 3 D008527 ClinicalTrials
Leukemia, Megakaryoblastic, Acute 3 D007947 ClinicalTrials
Leukemia, Myeloid, Acute 3 D015470 ClinicalTrials
Leukemia, Basophilic, Acute 3 D015471 ClinicalTrials
Anemia, Refractory 3 D000753 ClinicalTrials
Uterine Neoplasms 3 D014594 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Ovarian Neoplasms 3 D010051 ClinicalTrials
Multiple Sclerosis, Relapsing-Remitting 3 D020529 ClinicalTrials
Neuroectodermal Tumors, Primitive 3 D018242 ClinicalTrials
Triple Negative Breast Neoplasms 3 D064726 ClinicalTrials
Head and Neck Neoplasms 3 D006258 ClinicalTrials
Anemia, Aplastic 3 D000741 ClinicalTrials
Lymphoma, Mantle-Cell 3 D020522 ClinicalTrials
Anemia, Aplastic 3 D000741 ClinicalTrials
Amyloidosis, Familial 3 D028226 ClinicalTrials
Brain Neoplasms 3 D001932 ClinicalTrials
Myeloproliferative Disorders 3 D009196 ClinicalTrials
Adrenal Cortex Neoplasms 3 D000306 ClinicalTrials
Leukemia, Myelomonocytic, Chronic 3 D015477 ClinicalTrials
Liver Failure 3 D017093 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Leukemia, Erythroblastic, Acute 3 D004915 ClinicalTrials
Pheochromocytoma 3 D010673 ClinicalTrials
Myeloproliferative Disorders 3 D009196 ClinicalTrials
Anemia, Refractory, with Excess of Blasts 3 D000754 ClinicalTrials
Anemia 3 D000740 ClinicalTrials
Testicular Neoplasms 3 D013736 ClinicalTrials
Mediastinal Neoplasms 3 D008479 ClinicalTrials
Central Nervous System Neoplasms 3 D016543 ClinicalTrials
Mesenchymoma 3 D008637 ClinicalTrials
Sarcoma 3 D012509 ClinicalTrials
Fever 3 D005334 ClinicalTrials
Hot Flashes 3 D019584 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 D054198 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 D054198 ClinicalTrials
Urinary Bladder Neoplasms 3 D001749 ClinicalTrials
Brain Neoplasms 3 D001932 ClinicalTrials
Kidney Neoplasms 3 D007680 ClinicalTrials
Neoplasms, Germ Cell and Embryonal 3 D009373 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Ovarian Neoplasms 3 D010051 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 3 D064129 ClinicalTrials
Lung Neoplasms 3 D008175 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Endometrial Neoplasms 3 D016889 ClinicalTrials
Graft vs Host Disease 3 D006086 ClinicalTrials
Lymphoma, Follicular 3 D008224 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Leukemia-Lymphoma, Adult T-Cell 3 D015459 ClinicalTrials
Primary Ovarian Insufficiency 3 D016649 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Epidermolysis Bullosa Dystrophica 2 D016108 ClinicalTrials
Fanconi Anemia 2 D005199 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Uterine Cervical Neoplasms 2 D002583 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Lupus Erythematosus, Systemic 2 D008180 ClinicalTrials
Carcinoma 2 D002277 ClinicalTrials
Urethral Neoplasms 2 D014523 ClinicalTrials
Leukemia, Myeloid 2 D007951 ClinicalTrials
Anemia, Sickle Cell 2 D000755 ClinicalTrials
Esophageal Neoplasms 2 D004938 ClinicalTrials
Lymphoma, Large-Cell, Anaplastic 2 D017728 ClinicalTrials
Biliary Atresia 2 D001656 ClinicalTrials
Carcinoma, Islet Cell 2 D018273 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Nasopharyngeal Neoplasms 2 D009303 ClinicalTrials
Pemphigus 2 D010392 ClinicalTrials
Ischemic Stroke 2 D000083242 ClinicalTrials
Myelodysplastic-Myeloproliferative Diseases 2 D054437 ClinicalTrials
Breast Neoplasms, Male 2 D018567 ClinicalTrials
Lymphoma, T-Cell 2 D016399 ClinicalTrials
Leukemia, Mast-Cell 2 D007946 ClinicalTrials
Cerebral Palsy 2 D002547 ClinicalTrials
Inflammatory Breast Neoplasms 2 D058922 ClinicalTrials
Lymphoma, AIDS-Related 2 D016483 ClinicalTrials
Lymphopenia 2 D008231 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Wilms Tumor 2 D009396 ClinicalTrials
Sarcoma, Ewing 2 D012512 ClinicalTrials
Parkinson Disease 2 D010300 ClinicalTrials
Infertility 2 D007246 ClinicalTrials
Hematologic Diseases 2 D006402 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Neuromyelitis Optica 2 D009471 ClinicalTrials
Carcinoma, Squamous Cell 2 D002294 ClinicalTrials
Carcinoma, Hepatocellular 2 D006528 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Lymphoma, T-Cell, Peripheral 2 D016411 ClinicalTrials
Histiocytosis, Langerhans-Cell 2 D006646 ClinicalTrials
Amyotrophic Lateral Sclerosis 2 D000690 ClinicalTrials
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2 D015464 ClinicalTrials
Crohn Disease 2 D003424 ClinicalTrials
Peritoneal Neoplasms 2 D010534 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Cardiomyopathy, Dilated 2 D002311 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Red-Cell Aplasia, Pure 2 D012010 ClinicalTrials
Osteosarcoma 2 D012516 ClinicalTrials
Carcinoma, Renal Cell 2 D002292 ClinicalTrials
Small Cell Lung Carcinoma 2 D055752 ClinicalTrials
Stroke 2 D020521 ClinicalTrials
Blast Crisis 1 D001752 ClinicalTrials
Gliosarcoma 1 D018316 ClinicalTrials
Lymphoma, B-Cell, Marginal Zone 1 D018442 ClinicalTrials
Carcinoma, Endometrioid 1 D018269 ClinicalTrials
Neurilemmoma 1 D009442 ClinicalTrials
Sarcoma, Synovial 1 D013584 ClinicalTrials
Leukemia, Plasma Cell 1 D007952 ClinicalTrials
Primary Myelofibrosis 1 D055728 ClinicalTrials
Muscular Diseases 1 D009135 ClinicalTrials
Primary Myelofibrosis 1 D055728 ClinicalTrials
Severe Combined Immunodeficiency 1 D016511 ClinicalTrials
Cystadenoma, Serous 1 D018293 ClinicalTrials
Myasthenia Gravis 1 D009157 ClinicalTrials
Peripheral Arterial Disease 1 D058729 ClinicalTrials
Vasculitis 1 D014657 ClinicalTrials
Stiff-Person Syndrome 1 D016750 ClinicalTrials
Chordoma 1 D002817 ClinicalTrials
Menopause 1 D008593 ClinicalTrials
Multiple Sclerosis 1 D009103 ClinicalTrials
Coronary Disease 1 D003327 ClinicalTrials
Waldenstrom Macroglobulinemia 1 D008258 ClinicalTrials
Neoplasm Metastasis 1 D009362 ClinicalTrials
Leukemia, Promyelocytic, Acute 1 D015473 ClinicalTrials
Alzheimer Disease 1 D000544 ClinicalTrials
Enterocolitis, Necrotizing 1 D020345 ClinicalTrials
Lymphoma, B-Cell, Marginal Zone 1 D018442 ClinicalTrials
Liver Neoplasms 1 D008113 ClinicalTrials
Peripheral Vascular Diseases 0 D016491 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
16.83
Gastrointestinal disorders
8.9
Injury, poisoning and procedural complications
8.24
Blood and lymphatic system disorders
7.53
Investigations
6.71
Respiratory, thoracic and mediastinal disorders
6.67
Infections and infestations
6.27
Musculoskeletal and connective tissue disorders
5.65
Skin and subcutaneous tissue disorders
5.35
Nervous system disorders
4.81
Vascular disorders
4.29
Cardiac disorders
4.2
Metabolism and nutrition disorders
2.46
Immune system disorders
2.25

Cross References

Resources Reference
CAS NUMBER 121181-53-1
ChEMBL CHEMBL1201567
FDA SRS PVI5M0M1GW
Guide to Pharmacology 6968
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