GADOVERSETAMIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1999)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: V08CA06
UNII: RLM74T3Z9D

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H34GdN5O10
Molecular Weight 661.77
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
None Diagnostic agent FDA

Indications

Mesh Heading Maximum Phase Reference
Pathologic Processes Phase 4 ClinicalTrials

Side Effects from Label

Side effects Relative Frequency (%) Labels
General disorders and administration site conditions Discomfort 26.4
General disorders and administration site conditions Discomfort 23.0
General disorders and administration site conditions Discomfort 22.8
General disorders and administration site conditions Discomfort 12.0
Nervous system disorders Headache 9.42
Nervous system disorders Headache 9.4
Nervous system disorders Headache 8.4
Gastrointestinal disorders Dysgeusia 6.2
Gastrointestinal disorders Dysgeusia 6.19
Gastrointestinal disorders Dysgeusia 5.71
Surgical and medical procedures Vasodilation procedure 5.41
Nervous system disorders Headache 4.87
Gastrointestinal disorders Dysgeusia 4.86
Gastrointestinal disorders Dysgeusia 4.4
General disorders and administration site conditions Pain 3.95
Cardiac disorders Dizziness 3.74
Cardiac disorders Dizziness 3.7
Gastrointestinal disorders Nausea 3.21
Gastrointestinal disorders Nausea 3.2
Cardiac disorders Dizziness 3.1
General disorders and administration site conditions Injection site reaction 3.04
Cardiac disorders Dizziness 3.01
Gastrointestinal disorders Nausea 3.0
Gastrointestinal disorders Nausea 2.59
Gastrointestinal disorders Dysgeusia 2.53
General disorders and administration site conditions Asthenia 2.43
Gastrointestinal disorders Nausea 2.43
Surgical and medical procedures Vasodilation procedure 2.3
Nervous system disorders Paraesthesia 2.22
Nervous system disorders Paraesthesia 2.2
Skin and subcutaneous tissue disorders Dermatitis 2.13
Cardiac disorders Dizziness 2.13
Nervous system disorders Paraesthesia 2.13
Skin and subcutaneous tissue disorders Rash 2.13
Nervous system disorders Paraesthesia 2.1
Gastrointestinal disorders Diarrhoea 1.91
Gastrointestinal disorders Diarrhoea 1.9
General disorders and administration site conditions Pain 1.83
Surgical and medical procedures Vasodilation procedure 1.82
Cardiac disorders Dizziness 1.8
Nervous system disorders Paraesthesia 1.8
Gastrointestinal disorders Diarrhoea 1.74
Gastrointestinal disorders Nausea 1.74
General disorders and administration site conditions Asthenia 1.53
General disorders and administration site conditions Injection site reaction 1.53
Infections and infestations Rhinitis 1.53
Blood and lymphatic system disorders Ecchymosis 1.52
General disorders and administration site conditions Asthenia 1.5
General disorders and administration site conditions Pain 1.44
Surgical and medical procedures Vasodilation procedure 1.32
Musculoskeletal and connective tissue disorders Back pain 1.22
Gastrointestinal disorders Dyspepsia 1.22
General disorders and administration site conditions Pain 1.22
Infections and infestations Rhinitis 1.22
General disorders and administration site conditions Asthenia 1.2
Musculoskeletal and connective tissue disorders Back pain 1.2
General disorders and administration site conditions Injection site reaction 1.2
Nervous system disorders Paraesthesia 1.2
Infections and infestations Rhinitis 1.2
General disorders and administration site conditions Pain 1.02
General disorders and administration site conditions Pain 1.0
General disorders and administration site conditions Pain 0.993
Musculoskeletal and connective tissue disorders Back pain 0.962
Gastrointestinal disorders Dyspepsia 0.962
General disorders and administration site conditions Injection site reaction 0.962
Infections and infestations Rhinitis 0.962
Musculoskeletal and connective tissue disorders Back pain 0.912
Gastrointestinal disorders Diarrhoea 0.912
Skin and subcutaneous tissue disorders Dermatitis 0.902
Skin and subcutaneous tissue disorders Rash 0.902
General disorders and administration site conditions Asthenia 0.782
General disorders and administration site conditions Pain 0.782
Gastrointestinal disorders Diarrhoea 0.722
Blood and lymphatic system disorders Ecchymosis 0.661
Gastrointestinal disorders Dyspepsia 0.608
Musculoskeletal and connective tissue disorders Back pain 0.541
General disorders and administration site conditions Pain 0.481
Gastrointestinal disorders Dyspepsia 0.421
Skin and subcutaneous tissue disorders Dermatitis 0.361
Skin and subcutaneous tissue disorders Rash 0.361
Blood and lymphatic system disorders Ecchymosis 0.301

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Cardiac disorders
12.75
Nervous system disorders
10.86
Respiratory, thoracic and mediastinal disorders
10.01
Skin and subcutaneous tissue disorders
9.93
General disorders and administration site conditions
8.92
Vascular disorders
8.43
Gastrointestinal disorders
6.17
Musculoskeletal and connective tissue disorders
5.41
Metabolism and nutrition disorders
4.04
Injury, poisoning and procedural complications
3.71
Immune system disorders
3.35
Infections and infestations
3.23
Renal and urinary disorders
3.07
Ear and labyrinth disorders
2.58
Psychiatric disorders
2.34

Cross References

Resources Reference
CAS NUMBER 131069-91-5
ChEMBL CHEMBL1200457
FDA SRS RLM74T3Z9D
PubChem 444013
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