| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1982) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | Q3254X40X2 |
Structure
| InChI Key | REEUVFCVXKWOFE-UHFFFAOYSA-K |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C30H60I3N3O3 |
| Molecular Weight | 891.54 |
| AlogP | 5.45 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 21.0 |
| Polar Surface Area | 27.69 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 36.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| ANTAGONIST | Muscle-type nicotinic acetylcholine receptor antagonist | ISBN |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
- | 776 | - | 468-3715 | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 79 |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 65-29-2 |
| ChEMBL | CHEMBL1200993 |
| DrugBank | DB00483 |
| EPA CompTox | DTXSID5023089 |
| FDA SRS | Q3254X40X2 |
| Guide to Pharmacology | 356 |
| PDB | GMN |
| PubChem | 6172 |
| SureChEMBL | SCHEMBL249090 |
| ZINC | ZINC03830882 |
CONTENTS