| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1951) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt Prodrug |
| UNII: | 3X7931PO74 |
| Parent Compound: | HYDROCORTISONE |
Structure
| InChI Key | ALEXXDVDDISNDU-JZYPGELDSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H32O6 |
| Molecular Weight | 404.5 |
| AlogP | 2.35 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 100.9 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 29.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Secreted protein
|
- | - | - | 28 | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 91 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Dermatitis, Atopic | 2 | D003876 | ClinicalTrials |
| Vitiligo | 1 | D014820 | ClinicalTrials |
| Depressive Disorder | 0 | D003866 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 50-03-3 |
| ChEBI | 17609 |
| ChEMBL | CHEMBL1091 |
| DrugBank | DB14539 |
| DrugCentral | 4213 |
| FDA SRS | 3X7931PO74 |
| KEGG | C02821 |
| PubChem | 5744 |
| SureChEMBL | SCHEMBL7419 |
| ZINC | ZINC000003875333 |
CONTENTS