| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1984) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | L960UP2KRW |
| Parent Compound: | HYDROMORPHONE |
Structure
| InChI Key | XHILEZUETWRSHC-NRGUFEMZSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C17H20ClNO3 |
| Molecular Weight | 321.8 |
| AlogP | 1.63 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 0.0 |
| Polar Surface Area | 49.77 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 21.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Mu opioid receptor agonist | DailyMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Opioid receptor
|
1 | - | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Liver Diseases | 3 | D008107 | ClinicalTrials |
| Neoplasms | 3 | D009369 | ClinicalTrials |
| Back Pain | 3 | D001416 | ClinicalTrials |
| Chronic Pain | 3 | D059350 | ClinicalTrials |
| Osteoarthritis, Hip | 3 | D015207 | ClinicalTrials |
| Osteoarthritis, Knee | 3 | D020370 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 5791 |
| ChEMBL | CHEMBL1237055 |
| FDA SRS | L960UP2KRW |
| Guide to Pharmacology | 7082 |
| KEGG | C07042 |
| PubChem | 5462347 |
| SureChEMBL | SCHEMBL30521 |
| ZINC | ZINC00402954 |
CONTENTS