ICODEXTRIN

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Action	Mechanism of Action	Reference
None	Osmotic agent	DailyMed EMA

Mesh Heading	Maximum Phase	Mesh ID	Reference
Heart Failure	3	D006333	ClinicalTrials
Renal Insufficiency, Chronic	2	D051436	ClinicalTrials

Side effects	Relative Frequency (%)	Labels
Gastrointestinal disorders Peritonitis	26.0
Gastrointestinal disorders Peritonitis	25.0
Infections and infestations Upper respiratory tract infection	15.0
Vascular disorders Hypertension	13.0
Infections and infestations Upper respiratory tract infection	13.0
Skin and subcutaneous tissue disorders Dermatitis	10.0
Skin and subcutaneous tissue disorders Rash	10.0
Nervous system disorders Headache	9.0
Gastrointestinal disorders Abdominal pain	8.0
Gastrointestinal disorders Gastrointestinal pain	8.0
Vascular disorders Hypertension	8.0
Respiratory, thoracic and mediastinal disorders Cough	7.0
Nervous system disorders Headache	7.0
Infections and infestations Influenza	7.0
Gastrointestinal disorders Nausea	7.0
Gastrointestinal disorders Abdominal pain	6.0
Gastrointestinal disorders Gastrointestinal pain	6.0
Infections and infestations Influenza	6.0
Injury, poisoning and procedural complications Injury	6.0
General disorders and administration site conditions Oedema	6.0
Cardiac disorders Chest pain	5.0
Skin and subcutaneous tissue disorders Dermatitis	5.0
Gastrointestinal disorders Dyspepsia	5.0
Endocrine disorders Hyperglycaemia	5.0
Gastrointestinal disorders Nausea	5.0
General disorders and administration site conditions Oedema	5.0
Skin and subcutaneous tissue disorders Rash	5.0
Cardiac disorders Chest pain	4.0
Respiratory, thoracic and mediastinal disorders Cough	4.0
Gastrointestinal disorders Dyspepsia	4.0
Endocrine disorders Hyperglycaemia	4.0
Injury, poisoning and procedural complications Injury	4.0

System Organ Classification (SOC)

	Relative Frequency (%)
General disorders and administration site conditions	17.28
Infections and infestations	12.53
Gastrointestinal disorders	11.19
Vascular disorders	8.55
Cardiac disorders	8.42
Injury, poisoning and procedural complications	7.62
Metabolism and nutrition disorders	5.36
Respiratory, thoracic and mediastinal disorders	5.35
Nervous system disorders	4.35
Skin and subcutaneous tissue disorders	3.94
Investigations	3.29
Musculoskeletal and connective tissue disorders	2.99
Renal and urinary disorders	2.04

CONTENTS


Active Pharmaceutical Ingredients (APIs) Scaffolds	Exact Similarity SubStructure	Threshold (%) >= 70