LORACARBEF

Search structure
Trade Names:
Synonyms:
Status: Approved (1991)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: J01DC08
UNII: 3X11EVM5SU

Structure
InChI Key JAPHQRWPEGVNBT-UTUOFQBUSA-N
Smile N[C@@H](C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(Cl)CC[C@H]12)c1ccccc1
InChI
InChI=1S/C16H16ClN3O4/c17-9-6-7-10-12(15(22)20(10)13(9)16(23)24)19-14(21)11(18)8-4-2-1-3-5-8/h1-5,10-12H,6-7,18H2,(H,19,21)(H,23,24)/t10-,11-,12+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H16ClN3O4
Molecular Weight 349.77
AlogP 0.71
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 4.0
Polar Surface Area 112.73
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 24.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial penicillin-binding protein inhibitor DailyMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

Scaffolds

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Immune system disorders
83.33
Renal and urinary disorders
8.33
Nervous system disorders
2.78
Skin and subcutaneous tissue disorders
2.78
Vascular disorders
2.78

Cross References

Resources Reference
CAS NUMBER 76470-66-1
ChEMBL CHEMBL1200610
EPA CompTox DTXSID5048718
FDA SRS 3X11EVM5SU
PubChem 5284584
SureChEMBL SCHEMBL34152
CAS NUMBER 76470-66-1
ChEBI 47544
ChEMBL CHEMBL1013
DrugBank DB00447
DrugCentral 1603
EPA CompTox DTXSID7023223
FDA SRS W72I5ZT78Z
Human Metabolome Database HMDB0014590
PubChem 5284584
SureChEMBL SCHEMBL34153
ZINC ZINC000001530993
CONTENTS