MECLOCYCLINE SULFOSALICYLATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1982)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 46VZA7RX2B

Structure
InChI Key FYSVKUUNXYGFLA-CCHMMTNSSA-N
Smile C=C1c2c(Cl)ccc(O)c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12.O=C(O)c1cc(S(=O)(=O)O)ccc1O
InChI
InChI=1S/C22H21ClN2O8.C7H6O6S/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-5,10,14-15,17,26,28-30,33H,1H2,2-3H3,(H2,24,32);1-3,8H,(H,9,10)(H,11,12,13)/t10-,14-,15+,17+,22+;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H27ClN2O14S
Molecular Weight 695.06
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial 70S ribosome inhibitor PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
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Indications

Mesh Heading Maximum Phase Mesh ID Reference
Stomatitis 2 D013280 ClinicalTrials
Stomatitis 2 D013280 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 68555
ChEMBL CHEMBL261772
EPA CompTox DTXSID5045596
FDA SRS 46VZA7RX2B
KEGG C16199
SureChEMBL SCHEMBL193563
ZINC ZINC01680376
CONTENTS