MEPROBAMATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1955)
Entry Type: Small molecule
Molecule Category: Parent Metabolite
ATC: N05BC01
UNII: 9I7LNY769Q

Structure
InChI Key NPPQSCRMBWNHMW-UHFFFAOYSA-N
Smile CCCC(C)(COC(N)=O)COC(N)=O
InChI
InChI=1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H18N2O4
Molecular Weight 218.25
AlogP 0.98
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 6.0
Polar Surface Area 104.64
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 15.0

Pharmacology

Action Mechanism of Action Reference
AGONIST GABA-A receptor; anion channel agonist PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - -
Ion channel Ligand-gated ion channel GABA-A receptor
- - - - 2

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

MCS

Mixture
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Psychiatric disorders
20.59
Nervous system disorders
16.67
General disorders and administration site conditions
14.38
Injury, poisoning and procedural complications
13.4
Cardiac disorders
9.15
Respiratory, thoracic and mediastinal disorders
6.54
Vascular disorders
4.25
Gastrointestinal disorders
3.27

Cross References

Resources Reference
CAS NUMBER 57-53-4
ChEBI 6761
ChEMBL CHEMBL979
DrugBank DB00371
DrugCentral 1704
EPA CompTox DTXSID3023261
FDA SRS 9I7LNY769Q
Human Metabolome Database HMDB0014515
Guide to Pharmacology 7225
PharmGKB PA450377
PubChem 4064
SureChEMBL SCHEMBL15286
ZINC ZINC000001530701
CONTENTS