METHOHEXITAL SODIUM

Search structure
Trade Names:
Synonyms:
Status: Approved (1960)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 60200PNZ7Q
Parent Compound: METHOHEXITAL

Structure
InChI Key KDXZREBVGAGZHS-UHFFFAOYSA-M
Smile C=CCC1(C(C)C#CCC)C(=O)[N-]C(=O)N(C)C1=O.[Na+]
InChI
InChI=1S/C14H18N2O3.Na/c1-5-7-8-10(3)14(9-6-2)11(17)15-13(19)16(4)12(14)18;/h6,10H,2,5,9H2,1,3-4H3,(H,15,17,19);/q;+1/p-1

Physicochemical Descriptors

Property Name Value
Molecular Formula C14H17N2NaO3
Molecular Weight 284.29
AlogP 1.31
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 66.48
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 19.0

Pharmacology

Action Mechanism of Action Reference
POSITIVE ALLOSTERIC MODULATOR GABA-A receptor; anion channel positive allosteric modulator ISBN PubMed

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
43.3
Product issues
43.3
Respiratory, thoracic and mediastinal disorders
4.12
Injury, poisoning and procedural complications
3.09
Gastrointestinal disorders
2.06
Infections and infestations
2.06
Nervous system disorders
2.06

Cross References

Resources Reference
ChEBI 6834
ChEMBL CHEMBL30219
EPA CompTox DTXSID6026036
FDA SRS 60200PNZ7Q
PubChem 23690443
SureChEMBL SCHEMBL203151
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