METHYLTESTOSTERONE

Search structure
Trade Names:
Synonyms:
Status: Approved (1973)
Entry Type: Small molecule
Molecule Category: Parent
ATC: G03BA02
UNII: V9EFU16ZIF

Structure
InChI Key GCKMFJBGXUYNAG-HLXURNFRSA-N
Smile C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChI
InChI=1S/C20H30O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h12,15-17,22H,4-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H30O2
Molecular Weight 302.46
AlogP 4.27
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 0.0
Polar Surface Area 37.3
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 22.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Androgen Receptor agonist DailyMed
Primary Target
Androgen receptor
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Secreted protein
- - 4 - -
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 4
- 16 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Menopause 2 D008593 ClinicalTrials

Related Entries

MCS

Scaffolds

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Investigations
19.23
Injury, poisoning and procedural complications
15.38
Endocrine disorders
11.54
Metabolism and nutrition disorders
11.54
Respiratory, thoracic and mediastinal disorders
11.54
Cardiac disorders
7.69
Psychiatric disorders
7.69
Blood and lymphatic system disorders
3.85
General disorders and administration site conditions
3.85
Musculoskeletal and connective tissue disorders
3.85
Reproductive system and breast disorders
3.85

Cross References

Resources Reference
CAS NUMBER 58-18-4
ChEBI 27436
ChEMBL CHEMBL1395
DrugBank DB06710
DrugCentral 3356
EPA CompTox DTXSID1033664
FDA SRS V9EFU16ZIF
Human Metabolome Database HMDB0015655
Guide to Pharmacology 6945
KEGG C07198
PubChem 6010
SureChEMBL SCHEMBL18657
ZINC ZINC000003814422
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