Pharmacology

Action Mechanism of Action Reference
AGONIST Leptin receptor agonist FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Lipodystrophy 4 D008060 FDA
Obesity 3 D009765 ClinicalTrials
Lipodystrophy, Familial Partial 2 D052496 ClinicalTrials
Amenorrhea 2 D000568 ClinicalTrials
Insulin Resistance 2 D007333 ClinicalTrials
HIV-Associated Lipodystrophy Syndrome 2 D039682 ClinicalTrials
Non-alcoholic Fatty Liver Disease 2 D065626 ClinicalTrials
Metabolic Syndrome 2 D024821 ClinicalTrials
Diabetes Mellitus, Type 1 1 D003922 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Metabolism and nutrition disorders
14.75
General disorders and administration site conditions
13.05
Investigations
11.13
Gastrointestinal disorders
9.11
Injury, poisoning and procedural complications
7.45
Endocrine disorders
6.64
Infections and infestations
4.36
Hepatobiliary disorders
4.17
Skin and subcutaneous tissue disorders
3.92
Psychiatric disorders
3.66
Respiratory, thoracic and mediastinal disorders
2.83
Surgical and medical procedures
2.81
Vascular disorders
2.75
Nervous system disorders
2.07

Cross References

Resources Reference
CAS NUMBER 186018-45-1
ChEMBL CHEMBL2107857
FDA SRS TL60C27RLH
Guide to Pharmacology 7333