MIGALASTAT HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (2018)
Entry Type: Small molecule
Molecule Category: Salt
UNII: CLY7M0XD20
Parent Compound: MIGALASTAT

Structure
InChI Key ZJIHMALTJRDNQI-OLALXQGDSA-N
Smile Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O
InChI
InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H14ClNO4
Molecular Weight 199.63
AlogP -2.97
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 1.0
Polar Surface Area 92.95
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 11.0

Pharmacology

Action Mechanism of Action Reference
STABILISER Alpha-galactosidase A stabiliser FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Fabry Disease 4 D000795 FDA

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
15.89
Cardiac disorders
14.95
Respiratory, thoracic and mediastinal disorders
12.15
Nervous system disorders
11.21
Infections and infestations
6.54
Injury, poisoning and procedural complications
6.54
Vascular disorders
5.61
Psychiatric disorders
4.67
Surgical and medical procedures
4.67
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
3.74
Renal and urinary disorders
3.74
Gastrointestinal disorders
2.8
Investigations
2.8

Cross References

Resources Reference
ChEMBL CHEMBL2107355
FDA SRS CLY7M0XD20
PubChem 11644097
SureChEMBL SCHEMBL3802618
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