| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1996) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | A10BF02 |
| UNII: | 0V5436JAQW |
Structure
| InChI Key | IBAQFPQHRJAVAV-ULAWRXDQSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C8H17NO5 |
| Molecular Weight | 207.23 |
| AlogP | -3.26 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 5.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 104.39 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 14.0 |
Pharmacology
| Primary Target | |
|---|---|
| glucosidase alpha, acid | |
| maltase-glucoamylase |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Hydrolase
|
- | 590-1300 | - | 100000 | - | |
|
Enzyme
|
- | 110-39000 | - | 100000 | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 100 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Diabetes Mellitus, Type 1 | 3 | D003922 | ClinicalTrials |
Related Entries
MCS
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 72432-03-2 |
| ChEBI | 6935 |
| ChEMBL | CHEMBL1561 |
| DrugBank | DB00491 |
| DrugCentral | 1806 |
| EPA CompTox | DTXSID0023323 |
| FDA SRS | 0V5436JAQW |
| Human Metabolome Database | HMDB0014634 |
| Guide to Pharmacology | 4842 |
| KEGG | C07708 |
| PDB | MIG |
| PharmGKB | PA164776726 |
| PubChem | 441314 |
| SureChEMBL | SCHEMBL22593 |
| ZINC | ZINC000004097426 |
CONTENTS