| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1971) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | 0020414E5U |
| Parent Compound: | MINOCYCLINE |
Structure
| InChI Key | GLMUAFMGXXHGLU-VQAITOIOSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H28ClN3O7 |
| Molecular Weight | 493.94 |
| AlogP | 0.19 |
| Hydrogen Bond Acceptor | 9.0 |
| Hydrogen Bond Donor | 5.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 164.63 |
| Molecular species | ACID |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 33.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 101 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Periodontitis | 4 | D010518 | ClinicalTrials |
| Acne Vulgaris | 4 | D000152 | ClinicalTrials |
| Breast Neoplasms | 2 | D001943 | ClinicalTrials |
| Osteomyelitis | 0 | D010019 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 50697 |
| ChEMBL | CHEMBL1200881 |
| EPA CompTox | DTXSID8044545 |
| FDA SRS | 0020414E5U |
| KEGG | C07225 |
| SureChEMBL | SCHEMBL2537 |
| ZINC | ZINC14879992 |
CONTENTS