| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1999) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | C53598599T |
| Parent Compound: | MOXIFLOXACIN |
Structure
| InChI Key | IDIIJJHBXUESQI-DFIJPDEKSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C21H25ClFN3O4 |
| Molecular Weight | 437.9 |
| AlogP | 2.37 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 83.8 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 29.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Bacterial DNA gyrase inhibitor | DailyMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 106 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Bronchitis, Chronic | 4 | D029481 | ClinicalTrials |
| Pelvic Inflammatory Disease | 3 | D000292 | ClinicalTrials |
| Communicable Diseases | 3 | D003141 | ClinicalTrials |
| Graft vs Host Disease | 2 | D006086 | ClinicalTrials |
| Breast Neoplasms | 2 | D001943 | ClinicalTrials |
| Cataract | 1 | D002386 | ClinicalTrials |
| Muscular Dystrophy, Duchenne | 1 | D020388 | ClinicalTrials |
| Cystic Fibrosis | 1 | D003550 | ClinicalTrials |
| Osteomyelitis | 0 | D010019 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 7008 |
| ChEMBL | CHEMBL1200735 |
| EPA CompTox | DTXSID4045921 |
| FDA SRS | C53598599T |
| KEGG | D08237 |
| PDB | FX |
| PubChem | 101526 |
| SureChEMBL | SCHEMBL37285 |
| ZINC | ZINC03826253 |
CONTENTS