| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1985) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | A04AD11 |
| UNII: | 2N4O9L084N |
Structure
| InChI Key | GECBBEABIDMGGL-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H36O3 |
| Molecular Weight | 372.55 |
| AlogP | 6.26 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 46.53 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 27.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Cannabinoid CB1 receptor agonist | DailyMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Lipid-like ligand receptor (family A GPCR)
Cannabinoid receptor
|
16 | - | - | 4 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Postoperative Nausea and Vomiting | 4 | D020250 | ClinicalTrials |
| Postoperative Nausea and Vomiting | 4 | D020250 | ClinicalTrials |
| Diabetic Neuropathies | 3 | D003929 | ClinicalTrials |
| Parkinson Disease | 3 | D010300 | ClinicalTrials |
| Muscle Spasticity | 2 | D009128 | ClinicalTrials |
| Obesity | 2 | D009765 | ClinicalTrials |
| Suicidal Ideation | 2 | D059020 | ClinicalTrials |
| Fibromyalgia | 2 | D005356 | ClinicalTrials |
| Marijuana Abuse | 2 | D002189 | ClinicalTrials |
| Neuralgia | 2 | D009437 | ClinicalTrials |
| Obsessive-Compulsive Disorder | 1 | D009771 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Side Effects from Label
Side Effects (PT)
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 51022-71-0 |
| ChEBI | 135574 |
| ChEMBL | CHEMBL2218896 |
| DrugBank | DB00486 |
| DrugCentral | 1862 |
| FDA SRS | 2N4O9L084N |
| Guide to Pharmacology | 9071 |
| KEGG | D05099 |
| PubChem | 5284592 |
| SureChEMBL | SCHEMBL563809 |
| ZINC | ZINC01542930 |
CONTENTS