| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1971) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | MZ1131787D |
| Parent Compound: | NAPHAZOLINE |
Structure
| InChI Key | DJDFFEBSKJCGHC-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C14H15ClN2 |
| Molecular Weight | 246.74 |
| AlogP | 2.38 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 24.39 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 16.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Adrenergic receptor
|
12 | 0 | - | - | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 101 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Common Cold | 4 | D003139 | ClinicalTrials |
| Influenza, Human | 3 | D007251 | ClinicalTrials |
| Inflammation | 3 | D007249 | ClinicalTrials |
| Pterygium | 3 | D011625 | ClinicalTrials |
Related Entries
Adverse Reactions
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 7470 |
| ChEMBL | CHEMBL1706 |
| EPA CompTox | DTXSID7045788 |
| FDA SRS | MZ1131787D |
| Guide to Pharmacology | 7310 |
| KEGG | C07898 |
| PubChem | 11079 |
| SureChEMBL | SCHEMBL24153 |
| ZINC | ZINC00125006 |
CONTENTS