| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1973) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt Prodrug |
| UNII: | 9S44LIC7OJ |
| Parent Compound: | NORETHINDRONE |
Structure
| InChI Key | IMONTRJLAWHYGT-ZCPXKWAGSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H28O3 |
| Molecular Weight | 340.46 |
| AlogP | 4.06 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 43.37 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 25.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 105 |
Metabolites
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Endometriosis | 4 | D004715 | ClinicalTrials |
| Pain | 3 | D010146 | ClinicalTrials |
| Breast Neoplasms | 3 | D001943 | ClinicalTrials |
| Hemorrhage | 3 | D006470 | ClinicalTrials |
| Pregnancy | 3 | D011247 | ClinicalTrials |
| Leiomyoma | 3 | D007889 | ClinicalTrials |
| Lymphoma | 2 | D008223 | ClinicalTrials |
| Endometrial Hyperplasia | 2 | D004714 | ClinicalTrials |
| Cystic Fibrosis | 0 | D003550 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 7628 |
| ChEMBL | CHEMBL1201146 |
| DrugCentral | 1963 |
| EPA CompTox | DTXSID4023381 |
| FDA SRS | 9S44LIC7OJ |
| KEGG | C08152 |
| PubChem | 5832 |
| SureChEMBL | SCHEMBL37530 |
| ZINC | ZINC000001849528 |
CONTENTS