ORPHENADRINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1957)
Entry Type: Small molecule
Molecule Category: Salt
UNII: UBY910DUXH
Parent Compound: ORPHENADRINE

Structure
InChI Key UQZKYYIKWZOKKD-UHFFFAOYSA-N
Smile Cc1ccccc1C(OCCN(C)C)c1ccccc1.Cl
InChI
InChI=1S/C18H23NO.ClH/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;/h4-12,18H,13-14H2,1-3H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H24ClNO
Molecular Weight 305.85
AlogP 3.66
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 6.0
Polar Surface Area 12.47
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Glutamate [NMDA] receptor antagonist PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Psychiatric disorders
66.67
Injury, poisoning and procedural complications
16.67
Nervous system disorders
16.67

Cross References

Resources Reference
ChEBI 60902
ChEMBL CHEMBL1201023
EPA CompTox DTXSID5025815
FDA SRS UBY910DUXH
Guide to Pharmacology 7251
KEGG C07935
PubChem 9568
SureChEMBL SCHEMBL1235378
ZINC ZINC00155269
CONTENTS