OXANDROLONE

Search structure
Trade Names:
Synonyms:
Status: Approved (1964)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: A14AA08
UNII: 7H6TM3CT4L

Structure
InChI Key QSLJIVKCVHQPLV-PEMPUTJUSA-N
Smile C[C@]12COC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O
InChI
InChI=1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H30O3
Molecular Weight 306.45
AlogP 3.54
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 0.0
Polar Surface Area 46.53
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 22.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Androgen Receptor agonist
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - -
Enzyme Transferase
- - - - 9.859
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -0.33-13.86
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 4
- 0.808 - 62 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Wounds and Injuries 3 D014947 ClinicalTrials
Pressure Ulcer 3 D003668 ClinicalTrials
Turner Syndrome 3 D014424 ClinicalTrials
Neoplasms 3 D009369 ClinicalTrials
Klinefelter Syndrome 2 D007713 ClinicalTrials
Rotator Cuff Injuries 2 D000070636 ClinicalTrials
Burns 2 D002056 ClinicalTrials
Fanconi Anemia 1 D005199 ClinicalTrials
Malnutrition 1 D044342 ClinicalTrials

Related Entries

MCS

Scaffolds

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
22.73
Injury, poisoning and procedural complications
9.09
Nervous system disorders
9.09
Hepatobiliary disorders
6.82
Investigations
6.82
Musculoskeletal and connective tissue disorders
6.82
Eye disorders
4.55
Gastrointestinal disorders
4.55
Infections and infestations
4.55
Psychiatric disorders
4.55
Surgical and medical procedures
4.55
Vascular disorders
4.55
Cardiac disorders
2.27
Ear and labyrinth disorders
2.27
Endocrine disorders
2.27
Immune system disorders
2.27
Renal and urinary disorders
2.27

Cross References

Resources Reference
CAS NUMBER 53-39-4
ChEBI 7820
ChEMBL CHEMBL1200436
DrugBank DB00621
DrugCentral 2011
EPA CompTox DTXSID8023399
FDA SRS 7H6TM3CT4L
Human Metabolome Database HMDB14759
Guide to Pharmacology 7092
KEGG C07346
PharmGKB PA164749395
PubChem 5878
SureChEMBL SCHEMBL148881
ZINC ZINC000003813047
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