OXYGEN

Search structure
Trade Names:
Synonyms:
Status: Approved (2015)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: V03AN01
UNII: S88TT14065

Structure
InChI Key MYMOFIZGZYHOMD-UHFFFAOYSA-N
Smile O=O
InChI
InChI=1S/O2/c1-2

Physicochemical Descriptors

Property Name Value
Molecular Formula O2
Molecular Weight 32.0
AlogP 0.07
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 0.0
Polar Surface Area 34.14
Molecular species None
Aromatic Rings 0.0
Heavy Atoms 2.0

Pharmacology

Action Mechanism of Action Reference
None Essential for cellular homeostasis

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Vascular Diseases 3 D014652 ClinicalTrials
Coronary Disease 3 D003327 ClinicalTrials
Infections 3 D007239 ClinicalTrials
Ischemic Stroke 3 D000083242 ClinicalTrials
Postoperative Nausea and Vomiting 3 D020250 ClinicalTrials
Anemia, Sickle Cell 3 D000755 ClinicalTrials
Heart Failure 3 D006333 ClinicalTrials
Burns 3 D002056 ClinicalTrials
Schizophrenia 3 D012559 ClinicalTrials
Respiratory Distress Syndrome 3 D012128 ClinicalTrials
Hypertension, Pulmonary 3 D006976 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Premature Birth 3 D047928 ClinicalTrials
Ulcer 3 D014456 ClinicalTrials
Optic Neuropathy, Ischemic 3 D018917 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Complex Regional Pain Syndromes 3 D020918 ClinicalTrials
Bronchiolitis 3 D001988 ClinicalTrials
Retinopathy of Prematurity 3 D012178 ClinicalTrials
Pain 3 D010146 ClinicalTrials
Post-Acute COVID-19 Syndrome 3 D000094024 ClinicalTrials
Pregnancy 3 D011247 ClinicalTrials
Shock 3 D012769 ClinicalTrials
Pulmonary Embolism 3 D011655 ClinicalTrials
Hypertension, Pulmonary 3 D006976 ClinicalTrials
Pyoderma 3 D011711 ClinicalTrials
Acute Kidney Injury 3 D058186 ClinicalTrials
Fractures, Bone 3 D050723 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 3 D029424 ClinicalTrials
Diabetes Mellitus 3 D003920 ClinicalTrials
Carbon Monoxide Poisoning 3 D002249 ClinicalTrials
Wounds and Injuries 2 D014947 ClinicalTrials
Death, Sudden, Cardiac 2 D016757 ClinicalTrials
Idiopathic Pulmonary Fibrosis 2 D054990 ClinicalTrials
Colitis, Ulcerative 2 D003093 ClinicalTrials
Angina, Stable 2 D060050 ClinicalTrials
Multiple Myeloma 2 D009101 ClinicalTrials
Sleep Apnea, Obstructive 2 D020181 ClinicalTrials
Opioid-Related Disorders 2 D009293 ClinicalTrials
Tinea Pedis 2 D014008 ClinicalTrials
Gliosarcoma 2 D018316 ClinicalTrials
Osteoradionecrosis 2 D010025 ClinicalTrials
Carcinoma, Squamous Cell 2 D002294 ClinicalTrials
Child Development Disorders, Pervasive 2 D002659 ClinicalTrials
Status Asthmaticus 2 D013224 ClinicalTrials
Pulmonary Fibrosis 2 D011658 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Stroke 2 D020521 ClinicalTrials
Xerostomia 2 D014987 ClinicalTrials
Laryngeal Neoplasms 2 D007822 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Brain Injuries 2 D001930 ClinicalTrials
Endocarditis 2 D004696 ClinicalTrials
Brain Concussion 2 D001924 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Stress Disorders, Post-Traumatic 2 D013313 ClinicalTrials
Myocardial Infarction 2 D009203 ClinicalTrials
Migraine Disorders 2 D008881 ClinicalTrials
Lymphedema 2 D008209 ClinicalTrials
Cystitis, Hemorrhagic 2 D000096722 ClinicalTrials
Myocardial Ischemia 2 D017202 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Aging 2 D000375 ClinicalTrials
Tonsillitis 2 D014069 ClinicalTrials
Brain Neoplasms 2 D001932 ClinicalTrials
Hypoadrenocorticism, Familial 2 D000075262 ClinicalTrials
Anxiety 1 D001007 ClinicalTrials
Hypovolemia 1 D020896 ClinicalTrials
Autistic Disorder 1 D001321 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 1 D002289 ClinicalTrials
Diabetes Mellitus, Type 2 1 D003924 ClinicalTrials
Central Nervous System Neoplasms 1 D016543 ClinicalTrials
Ischemia 1 D007511 ClinicalTrials
Osteonecrosis 1 D010020 ClinicalTrials
Retinitis Pigmentosa 1 D012174 ClinicalTrials
Respiratory Insufficiency 1 D012131 ClinicalTrials
Inflammatory Bowel Diseases 1 D015212 ClinicalTrials
Reperfusion Injury 1 D015427 ClinicalTrials
Bell Palsy 1 D020330 ClinicalTrials
Neuralgia 1 D009437 ClinicalTrials
Lung Diseases 1 D008171 ClinicalTrials
Lung Neoplasms 1 D008175 ClinicalTrials
Hypoplastic Left Heart Syndrome 1 D018636 ClinicalTrials
Erectile Dysfunction 1 D007172 ClinicalTrials
Hypoxia 1 D000860 ClinicalTrials
Ileus 1 D045823 ClinicalTrials
Brain Diseases 1 D001927 ClinicalTrials
Spinal Cord Injuries 1 D013119 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Injury, poisoning and procedural complications
39.21
Eye disorders
9.5
Pregnancy, puerperium and perinatal conditions
8.51
Respiratory, thoracic and mediastinal disorders
7.92
Skin and subcutaneous tissue disorders
7.92
General disorders and administration site conditions
5.94
Product issues
4.16
Nervous system disorders
3.37
Vascular disorders
3.37
Cardiac disorders
2.97

Cross References

Resources Reference
CAS NUMBER 7782-44-7
ChEBI 15379
ChEMBL CHEMBL1234886
DrugBank DB09140
DrugCentral 4235
EPA CompTox DTXSID2037681
FDA SRS S88TT14065
Human Metabolome Database HMDB01377
KEGG C00007
PDB OXY
PubChem 977
SureChEMBL SCHEMBL821
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