| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1986) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | K89MJ0S5VY |
| Parent Compound: |
Structure
| InChI Key | BEEDODBODQVSIM-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C16H25ClN2O |
| Molecular Weight | 296.84 |
| AlogP | 2.85 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 44.62 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 19.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 105 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Rhinitis, Allergic, Seasonal | 4 | D006255 | ClinicalTrials |
| Erythema | 3 | D004890 | ClinicalTrials |
| Conjunctivitis, Allergic | 2 | D003233 | ClinicalTrials |
| Presbyopia | 2 | D011305 | ClinicalTrials |
Related Entries
Adverse Reactions
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 7863 |
| ChEMBL | CHEMBL1200791 |
| EPA CompTox | DTXSID80177729 |
| FDA SRS | K89MJ0S5VY |
| Guide to Pharmacology | 124 |
| KEGG | C07363 |
| PubChem | 66259 |
| SureChEMBL | SCHEMBL41247 |
| ZINC | ZINC00057435 |
CONTENTS