Trade Names:
Synonyms:
Status: Approved (2005)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: V03AF08
UNII: QMS40680K6

Pharmacology

Action Mechanism of Action Reference
AGONIST Fibroblast growth factor receptor 2 agonist PubMed FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Stomatitis 4 D013280 ClinicalTrials
Stomatitis 4 D013280 ClinicalTrials
Neoplasms 3 D009369 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Multiple Myeloma 3 D009101 ClinicalTrials
Head and Neck Neoplasms 3 D006258 ClinicalTrials
Carcinoma, Squamous Cell 3 D002294 ClinicalTrials
Leukemia 3 D007938 ClinicalTrials
Colonic Neoplasms 2 D003110 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Asthma 2 D001249 ClinicalTrials
Lymphoma, T-Cell 2 D016399 ClinicalTrials
Myelodysplastic Syndromes 2 D009190 ClinicalTrials
Leukemia, Myeloid, Acute 2 D015470 ClinicalTrials
Hodgkin Disease 1 D006689 ClinicalTrials
X-Linked Combined Immunodeficiency Diseases 1 D053632 ClinicalTrials
Graft vs Host Disease 1 D006086 ClinicalTrials
Stevens-Johnson Syndrome 1 D013262 ClinicalTrials
Graft vs Host Disease 1 D006086 ClinicalTrials
Lymphoma, Non-Hodgkin 1 D008228 ClinicalTrials
Leukemia, Plasma Cell 1 D007952 ClinicalTrials
Hematologic Neoplasms 1 D019337 ClinicalTrials
X-Linked Combined Immunodeficiency Diseases 1 D053632 ClinicalTrials
Multiple Sclerosis 1 D009103 ClinicalTrials
Neoplasms, Neuroepithelial 0 D018302 ClinicalTrials
Alopecia 0 D000505 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
21.15
Blood and lymphatic system disorders
7.69
Immune system disorders
7.69
Infections and infestations
7.69
Cardiac disorders
5.77
Gastrointestinal disorders
5.77
Respiratory, thoracic and mediastinal disorders
5.77
Vascular disorders
5.77
Hepatobiliary disorders
3.85
Injury, poisoning and procedural complications
3.85
Investigations
3.85
Metabolism and nutrition disorders
3.85
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
3.85
Renal and urinary disorders
3.85

Cross References

Resources Reference
CAS NUMBER 162394-19-6
ChEMBL CHEMBL1201821
FDA SRS QMS40680K6
Guide to Pharmacology 6954