PARGYLINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1982)
Entry Type: Small molecule
Molecule Category: Salt
UNII: W70V6I2OMY

Structure
InChI Key BCXCABRDBBWWGY-UHFFFAOYSA-N
Smile C#CCN(C)Cc1ccccc1.Cl
InChI
InChI=1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H14ClN
Molecular Weight 195.69
AlogP 1.75
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 3.0
Polar Surface Area 3.24
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 12.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Monoamine oxidase inhibitor PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Epigenetic regulator Eraser Lysine demethylase Lysine-specific demethylase
- - - - 69
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 134

Related Entries

Mixture

Cross References

Resources Reference
ChEMBL CHEMBL1200425
EPA CompTox DTXSID1044647
FDA SRS W70V6I2OMY
Guide to Pharmacology 7262
KEGG C07414
PubChem 9373
SureChEMBL SCHEMBL121111
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