PEGFILGRASTIM

Search structure
Trade Names:
Synonyms:
Status: Approved (2002)
Entry Type: Protein
Molecule Category: UNKNOWN
ATC: L03AA13
UNII: 3A58010674

Pharmacology

Action Mechanism of Action Reference
AGONIST Granulocyte colony stimulating factor receptor agonist

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Neoplasms 4 D009369 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Adrenal Cortex Neoplasms 3 D000306 ClinicalTrials
Endometrial Neoplasms 3 D016889 ClinicalTrials
Triple Negative Breast Neoplasms 3 D064726 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Multiple Myeloma 3 D009101 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 3 D016403 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Esophageal Neoplasms 3 D004938 ClinicalTrials
Neoplasms, Germ Cell and Embryonal 3 D009373 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 3 D064129 ClinicalTrials
Lung Neoplasms 3 D008175 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Uterine Neoplasms 3 D014594 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 3 D002289 ClinicalTrials
Sarcoma 3 D012509 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Fallopian Tube Neoplasms 2 D005185 ClinicalTrials
Urethral Neoplasms 2 D014523 ClinicalTrials
Leukemia, Myeloid 2 D007951 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Colonic Neoplasms 2 D003110 ClinicalTrials
Uterine Cervical Neoplasms 2 D002583 ClinicalTrials
Carcinoid Tumor 2 D002276 ClinicalTrials
Lymphoma, Non-Hodgkin 2 D008228 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Carcinoma, Squamous Cell 2 D002294 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 D054198 ClinicalTrials
Leukemia, Myeloid, Acute 2 D015470 ClinicalTrials
Carcinoma, Renal Cell 2 D002292 ClinicalTrials
Small Cell Lung Carcinoma 2 D055752 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Head and Neck Neoplasms 2 D006258 ClinicalTrials
Breast Neoplasms, Male 2 D018567 ClinicalTrials
Lymphoma, Mantle-Cell 2 D020522 ClinicalTrials
Myelodysplastic Syndromes 2 D009190 ClinicalTrials
Medulloblastoma 2 D008527 ClinicalTrials
Urinary Bladder Neoplasms 2 D001749 ClinicalTrials
Anemia, Aplastic 2 D000741 ClinicalTrials
Lymphoma, T-Cell, Peripheral 2 D016411 ClinicalTrials
Adenocarcinoma of Lung 2 D000077192 ClinicalTrials
Rectal Neoplasms 2 D012004 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Urinary Bladder Neoplasms 2 D001749 ClinicalTrials
Peritoneal Neoplasms 2 D010534 ClinicalTrials
Carcinoma, Islet Cell 2 D018273 ClinicalTrials
Neoplasms, Plasma Cell 2 D054219 ClinicalTrials
Carcinoma, Large Cell 2 D018287 ClinicalTrials
Testicular Neoplasms 2 D013736 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Nasopharyngeal Carcinoma 2 D000077274 ClinicalTrials
Leukemia 2 D007938 ClinicalTrials
Urinary Bladder Neoplasms 2 D001749 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Wilms Tumor 2 D009396 ClinicalTrials
Retinoblastoma 2 D012175 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Neuroblastoma 1 D009447 ClinicalTrials
Glioma 1 D005910 ClinicalTrials
Brain Neoplasms 1 D001932 ClinicalTrials
Lymphoma, T-Cell, Cutaneous 1 D016410 ClinicalTrials
Osteosarcoma 1 D012516 ClinicalTrials
Coronary Disease 1 D003327 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Injury, poisoning and procedural complications
29.19
General disorders and administration site conditions
17.18
Musculoskeletal and connective tissue disorders
5.68
Blood and lymphatic system disorders
5.26
Gastrointestinal disorders
4.78
Investigations
4.71
Skin and subcutaneous tissue disorders
4.41
Nervous system disorders
4.24
Product issues
4.14
Vascular disorders
3.66
Respiratory, thoracic and mediastinal disorders
3.54
Infections and infestations
2.09

Cross References

Resources Reference
CAS NUMBER 208265-92-3
ChEMBL CHEMBL1201568
FDA SRS 3A58010674
Guide to Pharmacology 6969
PubChem 119525
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