PHENACEMIDE

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Trade Names:
Synonyms:
Status: Approved (1951)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: N03AX07
UNII: PAI7J52V09

Structure
InChI Key XPFRXWCVYUEORT-UHFFFAOYSA-N
Smile NC(=O)NC(=O)Cc1ccccc1
InChI
InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13)

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H10N2O2
Molecular Weight 178.19
AlogP 0.42
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 2.0
Polar Surface Area 72.19
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 13.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sodium channel alpha subunit blocker Expert
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 105

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Cross References

Resources Reference
CAS NUMBER 63-98-9
ChEBI 8049
ChEMBL CHEMBL918
DrugBank DB01121
DrugCentral 2114
EPA CompTox DTXSID6023442
FDA SRS PAI7J52V09
Human Metabolome Database HMDB0015253
Guide to Pharmacology 7265
KEGG C07428
PharmGKB PA164745309
PubChem 4753
SureChEMBL SCHEMBL35118
ZINC ZINC000000001916
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