PHENDIMETRAZINE TARTRATE

Search structure


Trade Names:	ADPHEN ALPHAZINE BONTRIL BONTRIL PDM CAM-METRAZINE DI-METREX MELFIAT MELFIAT-105 METRA PHENAZINE PHENAZINE-35 PHENDIMETRAZINE TARTRATE PLEGINE SPRX-105 SPRX-3 STATOBEX STATOBEX-G X-TROZINE X-TROZINE L.A.
Synonyms:	Adipost Adphen Alphazine Appecon Azophenylene Bontril Bontril pdm Cam-metrazine Di-metrex Melfiat Melfiat-105 Metra NSC-13157 Phenazine Phenazine-35 Phendimetrazine bitartrate Phendimetrazine tartrate Phendimetrazine tartrate ciii Plegine Sprx-105 Sprx-3 Statobex Statobex-g X-trozine X-trozine l.a.
Status:	Approved (1976)
Entry Type:	Small molecule
Molecule Category:	Salt
UNII:	6985IP0T80
Parent Compound:	PHENDIMETRAZINE

Structure


InChI Key	VEPOHXYIFQMVHW-UHFFFAOYSA-N
Smile	CC1C(c2ccccc2)OCCN1C.O=C(O)C(O)C(O)C(=O)O
InChI	InChI=1S/C12H17NO.C4H6O6/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11;5-1(3(7)8)2(6)4(9)10/h3-7,10,12H,8-9H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C16H23NO7
Molecular Weight	341.36
AlogP	2.08
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	0.0
Number of Rotational Bond	1.0
Polar Surface Area	12.47
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	14.0

Pharmacology

Action	Mechanism of Action	Reference
INHIBITOR	Dopamine transporter inhibitor	PubMed FDA

Indications

Mesh Heading	Maximum Phase	Mesh ID	Reference

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution

System Organ Classification (SOC)

	Relative Frequency (%)
Cardiac disorders	22.12
General disorders and administration site conditions	15.93
Nervous system disorders	15.04
Psychiatric disorders	8.85
Vascular disorders	7.96
Eye disorders	5.31
Respiratory, thoracic and mediastinal disorders	4.42
Gastrointestinal disorders	3.54
Injury, poisoning and procedural complications	3.54
Skin and subcutaneous tissue disorders	3.54

Cross References

Resources	Reference
ChEMBL	CHEMBL2062163
FDA SRS	6985IP0T80
PubChem	120608

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