| Trade Names: | |
| Synonyms: | |
| Status: | Approved |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | MLF3D1712D |
Structure
| InChI Key | MBWXNTAXLNYFJB-NKFFZRIASA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C31H46O2 |
| Molecular Weight | 450.71 |
| AlogP | 9.16 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 14.0 |
| Polar Surface Area | 34.14 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 33.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Unclassified protein
|
- | 15000 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Cardiovascular Diseases | 3 | D002318 | ClinicalTrials |
| Osteoporosis | 3 | D010024 | ClinicalTrials |
| Glioblastoma | 2 | D005909 | ClinicalTrials |
| Renal Insufficiency, Chronic | 2 | D051436 | ClinicalTrials |
| Osteoporosis, Postmenopausal | 2 | D015663 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 1 | D064129 | ClinicalTrials |
| Cerebral Hemorrhage | 0 | D002543 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 18067 |
| ChEMBL | CHEMBL1550 |
| DrugBank | DB01022 |
| DrugCentral | 2843 |
| EPA CompTox | DTXSID8023472 |
| FDA SRS | MLF3D1712D |
| Human Metabolome Database | HMDB0004198 |
| PDB | PQN |
| SureChEMBL | SCHEMBL3882 |
| ZINC | ZINC000003831332 |
CONTENTS