PIPERACETAZINE

Search structure
Trade Names:
Synonyms:
Status: Approved (1969)
Entry Type: Small molecule
Molecule Category: UNKNOWN Prodrug
UNII: KL6248WNW4

Structure
InChI Key BTFMCMVEUCGQDX-UHFFFAOYSA-N
Smile CC(=O)c1ccc2c(c1)N(CCCN1CCC(CCO)CC1)c1ccccc1S2
InChI
InChI=1S/C24H30N2O2S/c1-18(28)20-7-8-24-22(17-20)26(21-5-2-3-6-23(21)29-24)13-4-12-25-14-9-19(10-15-25)11-16-27/h2-3,5-8,17,19,27H,4,9-16H2,1H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H30N2O2S
Molecular Weight 410.58
AlogP 4.98
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 43.78
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Dopamine D2 receptor antagonist
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - - 13.16
Enzyme Transferase
- - - -
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- 2187 - - 38.43-77.68

Related Entries

MCS

Scaffolds

Cross References

Resources Reference
ChEBI 92293
ChEMBL CHEMBL1584
DrugCentral 2186
EPA CompTox DTXSID7023481
FDA SRS KL6248WNW4
PubChem 19675
SureChEMBL SCHEMBL148569
ZINC ZINC000000538186
CONTENTS