PITAVASTATIN SODIUM

Search structure
Trade Names:
Synonyms:
Status: Approved (2017)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 29556RBN9P
Parent Compound: PITAVASTATIN

Structure
InChI Key NBDQGOCGYHMDSJ-NRFPMOEYSA-M
Smile O=C([O-])C[C@H](O)C[C@H](O)/C=C/c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.[Na+]
InChI
InChI=1S/C25H24FNO4.Na/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H23FNNaO4
Molecular Weight 443.45
AlogP 4.52
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 8.0
Polar Surface Area 90.65
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 31.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR HMG-CoA reductase inhibitor FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hyperlipidemias 4 D006949 FDA
Dyslipidemias 4 D050171 FDA

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
30.77
Musculoskeletal and connective tissue disorders
23.08
Immune system disorders
15.38
Respiratory, thoracic and mediastinal disorders
15.38
Skin and subcutaneous tissue disorders
15.38

Cross References

Resources Reference
ChEMBL CHEMBL3989920
FDA SRS 29556RBN9P
PubChem 23696934
SureChEMBL SCHEMBL15309107
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