POTASSIUM CHLORIDE

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Trade Names:	K+10 K+8 KAON CL KAON CL-10 K-LEASE KLOR-CON KLOR-CON M10 KLOR-CON M15 KLOR-CON M20 KLOTRIX K-TAB MICRO-K MICRO-K 10 MICRO-K LS POTASSIUM CHLORIDE POTASSIUM CHLORIDE 10MEQ IN PLASTIC CONTAINER POTASSIUM CHLORIDE 20MEQ IN PLASTIC CONTAINER POTASSIUM CHLORIDE 30MEQ IN PLASTIC CONTAINER POTASSIUM CHLORIDE 40MEQ IN PLASTIC CONTAINER POTASSIUM CHLORIDE IN PLASTIC CONTAINER SLOW-K TEN-K
Synonyms:	B1653 CHLORIDE (AS POTASSIUM) DIFFU-K DURO-K E 508 E-508 E508 INS-508 INS NO.508 K+10 K+8 KALEORID KALEORID LP KALII CHLORIDUM KALI MURIATICUM KAON CL KAON CL-10 KAY-CEE-L K-CONTIN K-DUR 20 K-LEASE KLOR-CON KLOR-CON 10 KLOR-CON 10MEQ KLOR-CON 8 KLOR-CON M10 KLOR-CON M15 KLOR-CON M20 KLOREF KLOREF-S KLOTRIX K-TAB LEO K MICRO K MICRO-K MICRO-K 10 MICRO-K LS NEOBAKASAL NSC-77368 NU-K POKONZA POTASSIUM (AS CHLORIDE) POTASSIUM CHLORIDE COMPONENT OF COLYTE POTASSIUM CHLORIDE COMPONENT OF GOLYTELY POTASSIUM CHLORIDE COMPONENT OF HALFLYTELY POTASSIUM CHLORIDE COMPONENT OF MOVIPREP POTASSIUM CHLORIDE COMPONENT OF NAVSTEL POTASSIUM CHLORIDE COMPONENT OF NULYTELY POTASSIUM CHLORIDE COMPONENT OF PLENVU POTASSIUM CHLORIDE COMPONENT OF PROCALAMINE POTASSIUM CHLORIDE COMPONENT OF SUCLEAR POTASSIUM CHLORIDE COMPONENT OF SUFLAVE POTASSIUM CHLORIDE COMPONENT OF SUTAB POTASSIUM CHLORIDE COMPONENT OF THAM-E POTASSIUM CHLORIDE COMPONENT OF TIS-U-SOL POT CHLOR (POT 12MMOL) POT CHLOR STRONG SANDO-K SLOW-K SYLVINE SYLVITE TEN-K
Status:	Approved
Entry Type:	Small molecule
Molecule Category:	Salt
ATC:	A12BA01
UNII:	660YQ98I10
Parent Compound:	POTASSIUM

Structure


InChI Key	WCUXLLCKKVVCTQ-UHFFFAOYSA-M
Smile	[Cl-].[K+]
InChI	InChI=1S/ClH.K/h1H;/q;+1/p-1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	ClK
Molecular Weight	74.55
AlogP	None
Hydrogen Bond Acceptor	None
Hydrogen Bond Donor	None
Number of Rotational Bond	None
Polar Surface Area	None
Molecular species	None
Aromatic Rings	None
Heavy Atoms	None

Pharmacology

Action	Mechanism of Action	Reference
None	Supplement

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Lyase	-	-	-	156000000	-
Membrane receptor Taste family G protein-coupled receptor Taste receptor (taste family GPCR)	5000000	-	-	-	-
Unclassified protein	174000000	-	-	-	-

Indications

Mesh Heading	Maximum Phase	Mesh ID	Reference
Heart Diseases	3	D006331	ClinicalTrials
Angina, Unstable	3	D000789	ClinicalTrials
Constipation	3	D003248	ClinicalTrials
Hypertension	3	D006973	ClinicalTrials
Heart Failure	3	D006333	ClinicalTrials
Heart Failure	3	D006333	ClinicalTrials
Myocardial Infarction	3	D009203	ClinicalTrials
Coronary Disease	3	D003327	ClinicalTrials
Aortic Valve Stenosis	2	D001024	ClinicalTrials
Brain Neoplasms	2	D001932	ClinicalTrials
Heart Arrest	2	D006323	ClinicalTrials
Heart Failure, Diastolic	2	D054144	ClinicalTrials
Shock, Septic	1	D012772	ClinicalTrials

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Adverse Reactions

SOC By Demographic Distribution

System Organ Classification (SOC)

	Relative Frequency (%)
Gastrointestinal disorders	14.03
General disorders and administration site conditions	13.36
Nervous system disorders	9.61
Injury, poisoning and procedural complications	7.18
Respiratory, thoracic and mediastinal disorders	7.16
Psychiatric disorders	6.66
Investigations	6.62
Cardiac disorders	6.43
Musculoskeletal and connective tissue disorders	4.61
Metabolism and nutrition disorders	4.31
Vascular disorders	4.23
Immune system disorders	4.07
Skin and subcutaneous tissue disorders	4.02

Cross References

Resources	Reference
CAS NUMBER	7447-40-7
ChEBI	32588
ChEMBL	CHEMBL1200731
DrugBank	DB00761
EPA CompTox	DTXSID5021178
FDA SRS	660YQ98I10
PharmGKB	PA451055
PubChem	4873
SureChEMBL	SCHEMBL4925

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