PRALIDOXIME CHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1964)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 38X7XS076H
Parent Compound: PRALIDOXIME

Structure
InChI Key HIGSLXSBYYMVKI-UHFFFAOYSA-N
Smile C[n+]1ccccc1/C=N/O.[Cl-]
InChI
InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C7H9ClN2O
Molecular Weight 172.61
AlogP 0.32
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 36.47
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 10.0

Pharmacology

Action Mechanism of Action Reference
ACTIVATOR Acetylcholinesterase activator
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 366000-1210000 17770-3159000 126500 4-38
Enzyme Transferase
- 184700 - - -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Acetylcholine receptor
- 170000 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Parent
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Blood and lymphatic system disorders
30.57
Surgical and medical procedures
12.03
Vascular disorders
11.64
Injury, poisoning and procedural complications
11.05
Nervous system disorders
9.47
General disorders and administration site conditions
5.52
Respiratory, thoracic and mediastinal disorders
5.13
Infections and infestations
3.35

Cross References

Resources Reference
ChEBI 8355
ChEMBL CHEMBL748
EPA CompTox DTXSID1023495
FDA SRS 38X7XS076H
PubChem 45006123
SureChEMBL SCHEMBL61419
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